Amelioration of bleomycin-induced lung fibrosis in hamsters by dietary supplementation with taurine and niacin: biochemical mechanisms. [PDF]
, 1994 Interstitial pulmonary fibrosis induced by intratracheal instillation of bleomycin (BL) involves an excess production of reactive oxygen species, unavailability of adequate levels of NAD and ATP to repair the injured pulmonary epithelium, and an ...
Chandler DB +34 more
core +2 more sources
Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung [PDF]
, 2013 Phagocytes not only coordinate acute inflammation and host defense at mucosal sites, but also contribute to tissue damage. Respiratory infection causes a globally significant disease burden and frequently progresses to acute respiratory distress syndrome,
A Cross +58 more
core +1 more source
IL-1R and inflammasomes mediate early pulmonary protective mechanisms in respiratory brucella abortus infection [PDF]
, 2016 Brucella spp. infection is frequently acquired through contaminated aerosols. The role of interleukin-1 beta (IL-1β) in the early pulmonary response to respiratory Brucella infection is unknown.
Alonso Paiva, Iván Mathias +9 more
core +1 more source
Nursing Open, 2023 Aims This study was performed to identify and summarize systematic reviews focusing on the prevention of unplanned endotracheal extubation in the intensive care unit. Design Overview of systematic reviews. Methods This overview was conducted according to
Jinhua Wu +6 more
doaj +1 more source
Investigation of the cytotoxicity of CCVD carbon nanotubes towards human umbilical vein endothelial cells [PDF]
, 2006 The cytotoxicity of different samples of carbon nanotubes synthesised by catalytic chemical vapour deposition was investigated towards human umbilical vein endothelial cells, using two cytotoxicity standard assays (neutral red assay for the cell ...
Baquey, Charles +4 more
core +1 more source
MicroRNA-483 amelioration of experimental pulmonary hypertension. [PDF]
, 2020 Endothelial dysfunction is critically involved in the pathogenesis of pulmonary arterial hypertension (PAH) and that exogenously administered microRNA may be of therapeutic benefit.
Bai, Liang +22 more
core +1 more source
Oman Medical Journal, 2021 Objectives: We sought to identify the chest radiography differences at presentation between two groups of hospitalized confirmed COVID-19 patients; intubated group compared to non-intubated group.
Faiza A. Al Kindi +6 more
doaj +1 more source
Acute inflammatory response to contrast agent aspiration and its mechanisms in the rat lung. [PDF]
, 2019 Objectives/hypothesisContrast agent (CA) aspiration is an established complication of upper gastrointestinal and videofluoroscopic swallow studies. The underlying molecular biological mechanisms of acute response to CA aspiration in the respiratory ...
Belafsky, Peter C +6 more
core +1 more source
Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice. [PDF]
, 2016 Background: P. aeruginosa is one of the top three causes of opportunistic human bacterial infections. The remarkable variability in the clinical outcomes of this infection is thought to be associated with genetic predisposition.
A Bragonzi +62 more
core +1 more source
Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury [PDF]
, 2005 Acute respiratory distress syndrome (ARDS) usually requires symptomatic supportive therapy by intubation and mechanical ventilation with the supplemental use of high oxygen concentrations.
+62 more
core +5 more sources