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Intratympanic Gentamicin Treatment for Meniere's Disease
Otolaryngology–Head and Neck Surgery, 1998OBJECTIVESThe purpose of this study was to evaluate the safety and efficacy of a modified intratympanic gentamicin technique in patients with intractable unilateral or bilateral Meniere's disease.METHODSA retrospective review of 25 consecutive patients who underwent gentamicin treatment for Meniere's disease was conducted between 1992 and 1996.
Patrick J. Antonelli +3 more
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Intratympanic aminoglycosides for Ménière’s disease
Cochrane Database of Systematic Reviews, 2021Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the benefits and harms of intratympanic destructive interventions (aminoglycosides) for Ménière's disease.
Webster, Katie E. +8 more
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Intratympanic gentamicin for Ménière's disease or syndrome
Cochrane Database of Systematic Reviews, 2010Ménière's disease is characterised by three major symptoms: vertigo, deafness and tinnitus, which may be accompanied by aural fullness, all of which are discontinuous and variable in intensity. While discontinuous, these symptoms are synchronous. Intratympanic application of gentamicin, an ototoxic aminoglycoside, is a relatively new ablative treatment
Peter Paul G. van Benthem, Bas Pullens
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Intratympanic injection in delayed endolymphatic hydrops
Acta Oto-Laryngologica, 2015The present study showed that intratympanic dexamethasone injection (ITD) is a promising approach for the treatment of contralateral and ipsilateral delayed endolymphatic hydrops (DEH). Moreover, intratympanic gentamicin injection (ITG), as a chemical labyrinthectomy, is a simple alternative for controlling vertigo in patients with ipsilateral DEH.This
Weijia Kong +5 more
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Intratympanic methylprednisolone injections for subjective tinnitus
The Journal of Laryngology & Otology, 2009AbstractObjectives:This study aimed to determine whether intratympanically injected methylprednisolone is effective in treating subjective tinnitus refractory to medical treatment.Study design:Prospective, randomised, placebo-controlled, single-blinded study.Methods:Seventy adult patients with subjective tinnitus of cochlear origin were randomly ...
A Sahin-Yilmaz +5 more
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Intratympanic and Systemic Dexamethasone for Ménière’s Disease
ORL, 2000Intratympanic and systemic dexamethasone treatment of Ménière’s disease (MD) was evaluated in a prospective study. Seventeen patients (6 men and 11 women) with MD (5 right-sided, 11 left-sided and 1 bilateral) were treated with three 0.2- to 0.4-ml injections of intratympanic dexamethasone hyaluronate (16 mg/ml) during a week and with an initial ...
Timo P. Hirvonen +2 more
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Intratympanic steroids for Ménière's disease or syndrome
Cochrane Database of Systematic Reviews, 2010Ménière's disease is a disorder characterised by hearing loss, tinnitus and disabling vertigo. The use of intratympanic steroids to reduce the severity of these symptoms has been gaining popularity.To assess the effectiveness of intratympanic steroids on the frequency and severity of attacks of vertigo, on chronic symptoms such as tinnitus, imbalance ...
Brian D. Westerberg, John S. Phillips
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Intratympanic Methylprednisolone for Sudden Sensorineural Hearing Loss
Otology & Neurotology, 2007Corticosteroids are commonly used for the treatment of sudden sensorineural hearing loss (SSHL). In this study, the effectiveness of intratympanic (IT) corticosteroid injection was studied and compared with a control group on patients with SSHL who failed systemic corticosteroid treatment.A total of 19 patients as a retreatment group (RG) and 18 ...
Kilic, Rahmi +6 more
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Intratympanic keratoma following grommet insertion
The Journal of Laryngology & Otology, 1976An intratympanic keratoma following myringotomy and multiple Shepard's grommet insertions is presented.
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The history of intratympanic drug therapy in otology
Otolaryngologic Clinics of North America, 2004The application of drugs through the eardrum and into the middle ear to treat various otologic disorders has recently gained wide-spread popularity. Despite the relatively recent interest in this technique, if one considers any application of medication into the middle ear as intratympanic therapy, the roots of this method can really be considered to ...
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