Results 31 to 40 of about 668,827 (125)
Mesna in Otologic Surgery: Efficacy and Safety—A Scoping Review
The Laryngoscope, Volume 136, Issue 6, Page 2449-2460, June 2026.PRISMA flow diagram indicating the process of systematic inclusion and exclusion of articles. ABSTRACT Objective Mesna (Sodium 2‐mercaptoethanesulfonate) is widely used as a mucolytic agent and uroprotective agent. Recently, its disulfide bond‐breaking property has been applied in otologic surgery to facilitate safer dissection of cholesteatoma and ...
Kevork H. Atamian +4 more
wiley +1 more source
, 2020 Objective: To compare the effect of injection time intervals of intratympanic (IT) dexamethasone (DEX) in patients with idiopathic sudden sensorineural hearing loss (ISSNHL).
송찬일
core +1 more source
Advances in GPCRs Associated With Wnt Signaling Within the Auditory System
Medicine Bulletin, Volume 2, Issue 3, Page 280-298, June 2026.ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang +3 more
wiley +1 more source
Effectiveness of intratympanic administration of gentamicin in unilateral menière’s disease
, 2020 To the Editor: In a recent issue published by Otology and Neurotology, Yaz et al. (1) presented an interesting work to analyze the effectiveness of an intratympanic (IT) injection of aminoglycosides compared to intratympanic corticosteroids to ...
Gioacchini F. M. +6 more
core +1 more source
A COMPARATIVE STUDY ON EFFICACY OF ORAL AND INTRATYMPANIC STEROIDS IN SUBJECTIVE IDIOPATHIC TINNITUS
, 2022 Background: Tinnitus is a common and annoying symptom caused by an abnormal spontaneous activity from within the auditory system. Corticosteroids is used as an empirical treatment in the oral form or as intratympanic injection for the treatment of this ...
Dhinakaran Natarajan , Vijay Babu and Rhea Anna Kurian
core +1 more source
Noise‐Induced Hearing Loss: From Pathological Mechanisms to Therapeutic Interventions
Sensory Neuroscience, Volume 2, Issue 2, June 2026.ABSTRACT Noise‐induced hearing loss (NIHL), a significant non‐genetic form of hearing impairment, is primarily managed through the use of hearing aids and cochlear implants. However, the fundamental pathological mechanisms underlying NIHL remain inadequately addressed.
Shiqi Huang +7 more
wiley +1 more source
Progress On Sensorineural Hearing Loss: Mechanisms and Therapies
Sensory Neuroscience, Volume 2, Issue 2, June 2026.ABSTRACT Hearing loss is the most common disabling disease among humans, which adversely affects human health. Sensorineural hearing loss (SNHL) accounting for approximately 63% of all hearing loss cases. SNHL may be classified into age‐related hearing loss (ARHL), drug‐induced hearing loss (DIHL), noise‐induced hearing loss (NIHL), and sudden ...
Yuan Zhang +9 more
wiley +1 more source
AMPKα Silencing Prevents Kanamycin‐Induced Ototoxicity in an Acute Mouse Model
Sensory Neuroscience, Volume 2, Issue 2, June 2026.Kanamycin plus furosemide (KM + FU) treatment (acute ototoxic model) causes AMPKα activation and rapidly induces cochlear outer hair cell (OHC) loss. Silencing AMPKα1 via posterior semicircular canal injection 48 h before KM + FU treatment reduces this damage, preserving OHCs and hearing.
Shengyu Zou +6 more
wiley +1 more source
Migraine Features in Patients With Sudden Sensorineural Hearing Loss
Otolaryngology–Head and Neck Surgery, Volume 174, Issue 5, Page 1263-1269, May 2026.Abstract Objective To investigate the prevalence of migraine features among patients with sudden sensorineural hearing loss (SSNHL) and evaluate potential clinical associations. Study Design Retrospective survey‐based study. Setting Single institution tertiary care center. Methods 168 adult patients with SSNHL were recruited.
Yalda Yazdani +5 more
wiley +1 more source
Advanced Sensor Research, Volume 5, Issue 4, April 2026.Sensorineural hearing loss (SNHL) occurs in 1.5 billion globally, primary driven by damage of cochlear hair cells and spiral ganglion neurons. This review systematically examines current therapeutic strategies for sensorineural hearing loss, including traditional drug and physical therapies as well as emerging stem cell and gene therapies, providing a ...
Ruirui Chen +3 more
wiley +1 more source