Results 21 to 30 of about 668,827 (125)
The aim of this study is to present a patient who developed a pneumolabyrinth following intratympanic steroid injection performed one year after stapes surgery. The patient started a medical treatment but since no improvement of his symptoms occurred, 10
L. Cagnoni +4 more
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Intratympanic Methylprednisolone Injection as First Line Therapy for Idiopathic Sudden Sensorineural Hearing Loss [PDF]
Introduction Steroid therapy is considered to be the gold standard for sudden sensorineural hearing loss (SSNHL). Delivering steroids by intratympanic injection is more efficient than systemic injections with minimum or no side effects.
Mukul Patar, Rupanjita Sangma
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Effect of Intratympanic Dexamethasone in Idiopathic Sudden Sensorineural Hearing Loss [PDF]
Introduction Oral steroids currently represent the standard treatment for idiopathic sudden sensorineural hearing loss The aim of this study is to assess the effectiveness of intratympanic dexamethasone injection for treating ‘Idiopathic sudden sensori ...
Bina Tamang +4 more
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A patient‐specific, imaging‐guided aid enables precise and reproducible drug delivery to the inner ear. By guiding therapeutic agents directly to the round window niche, this approach reduces variability in drug localization, improves delivery safety, and addresses a critical bottleneck in inner ear therapy, offering a scalable strategy for precision ...
Yanjing Luo +4 more
wiley +1 more source
Paeonol protects against cisplatin‐ and noise‐induced hearing loss by mitigating oxidative damage and preserving protein homeostasis in cochlear hair cells, revealing a novel mechanism involving ribosome biogenesis. ABSTRACT Background Hearing loss primarily results from irreversible cochlear hair cell (HC) damage caused by factors such as noise, aging,
Minhui Xia +8 more
wiley +1 more source
Comparative Study of Tympanic Membrane Regeneration Therapy for Chronic Otitis Media
This study compared tympanic membrane regeneration therapy (TMRT) with conventional tympanoplasty (CTP) for the treatment of chronic suppurative perforated otitis media (COM). TMRT has many advantages over CTP as a surgical treatment for COM. In particular, significant differences were observed in operative time, hearing improvement, and patient ...
Shin‐ichi Kanemaru +8 more
wiley +1 more source
Intratympanic treatment for tinnitus: A review
Since the 1940s, various attempts have been made to treat peripheral tinnitus by way of intratympanic injection. This administration procedure requires only low concentrations of medication, thanks to the highly targeted delivery to the site of action ...
Thomas Meyer
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Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley +1 more source
Intratympanic Gentamicin Injection for Endolymphatic Hydrops After Cochlear Implantation
Endolymphatic hydrops has been documented as a possible complication of cochlear implantation; however, few studies have addressed its treatment.
Ilaria Ottoboni +19 more
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BACKGROUND: Tinnitus is a common and distressing symptom which is characterized by the perceived sensation of sound without any corresponding external stimulus.
Selvapriya, E
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