Results 61 to 70 of about 2,272,470 (209)

The Baboon as a Model to Study Human Health and Complex Disease

American Journal of Primatology, Volume 88, Issue 9, September 2026.
Baboons remain underappreciated as models of human biology and disease offering a distinct combination of biological and practical properties. In this review, we evaluate the baboon as a model for human complex diseases and make the case for broader use of baboons in translational research.
Brittany Hazzard, Yoav Gilad
wiley   +1 more source

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

BMEMat, Volume 4, Issue 3, September 2026.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen, Jianfeng Wu, Shunhan Zhang, Siqi Huang, Yingjun Xie, Hongda Chen, Yinghong Yang, Lan Xiao, Ding Wang, Keke Wu, Xiaofang Sun   +10 more
wiley   +1 more source

Intrauterine deposition of calcium on copper-bearing intrauterine contraceptive devices. [PDF]

BMJ, 1977
Copper-bearing intrauterine contraceptive devices (IUDs) removed after various times in utero were examined by scanning electron microscopy and x-ray microanalysis of the elements present. As time in utero increased these devices became increasingly calcified. This calcification may limit the release of copper from the devices and decrease the specific
C, Gosden, A, Ross, N B, Loudon
openaire   +2 more sources

Biological evaluation of the copper/low-density polyethylene nanocomposite intrauterine device. [PDF]

PLoS ONE, 2013
Devices and materials intended for clinical applications as medical and implant devices should be evaluated to determine their biocompatibility in physiological systems.
Li-Xia Hu, Jing He, Li Hou, Hong Wang, Jun Li, Changsheng Xie, Zhuo Duan, Li-Kui Sun, Xin Wang, Changhong Zhu   +9 more
doaj   +1 more source

Use of hydrophilic pharmaceutical excipients to modulate release of metal ions from silicone elastomers

Drug Delivery
Silicone elastomers based on polydimethylsiloxane are biocompatible and non-biodegradable thermosetting polymers used in various drug delivery applications, including subdermal implants, vaginal rings, and intrauterine devices.
Xin Shen, Xinyu Zhao, Clare F. McCoy, Yahya H. Dallal Bashi, Peter Boyd, R. Karl Malcolm   +5 more
doaj   +1 more source

Discontinuation rates of intrauterine contraception due to unfavourable bleeding: a systematic review

BMC Women's Health, 2022
Objective Levonorgestrel-releasing intrauterine devices (LNG-IUDs) and copper intrauterine devices (Cu-IUDs) offer long-acting contraception; however, some women may discontinue use within the first year due to bleeding pattern changes, limiting their ...
Dustin Costescu, Rajinder Chawla, Rowena Hughes, Stephanie Teal, Martin Merz   +4 more
doaj   +1 more source

Contraceptive Alignment: A Descriptive Study of Concordance between Preferred and Actual Contraceptive Method Use

Studies in Family Planning, Volume 57, Issue 3, Page 309-330, September 2026.
Abstract Conventional metrics of contraceptive need focus on contraceptive use among those not seeking pregnancy, ignoring individuals’ contraceptive preferences beyond pregnancy prevention. We examine contraceptive alignment, a novel metric describing agreement between actual and preferred method use/nonuse, among a 2022 nationally representative U.S.
Stephanie Arteaga, Ariana H. Bennett, Anu Manchikanti Gomez   +2 more
wiley   +1 more source

Preparation and Characterization of Polyurethane/Nanocopper Composites and Their Application in Intrauterine Devices [PDF]

, 2020
A novel intrauterine devices material, polyurethane/nano-copper (PU/NC) nanocomposite, was prepared. The structure, morphology, copper ion (Cu 2+ ) release rate, and water absorption of PU/NC nanocomposites were investigated.
Zhixin Jia, Demin Jia, Yongjun Chen, Yuanfang Luo, Jue Wang   +4 more
core  

Single center experience on implementation of the postpartum intrauterine device (PPIUD) in Sri Lanka: a retrospective study

BMC Research Notes, 2020
Objectives to study the institutionalization of PPIUD services at Teaching Hospital, Mahamodara, Galle (THMG) and to study the feasibility, challenges and barriers for implementation. Results Total of 46,815 deliveries had occurred in the facility during
D. L. W. Dasanayake, M. Patabendige, Y. Amarasinghe   +2 more
doaj   +1 more source

Uncovering Modifiable Contributors to Depressive Symptoms During Antidepressant Prescription Renewal: A Primary Care Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Depressive symptoms in primary care often arise from a complex interplay of hormonal, biological, metabolic, psychosocial, and lifestyle factors. We present the case of a 41‐year‐old woman whose depressive symptoms began three months postpartum after her second pregnancy and persisted for approximately five years.
Leonora Muhadri, Hong Phan
wiley   +1 more source