Results 101 to 110 of about 115,374 (234)

Bridging the gap in obesity research: A consensus statement from the European Society for Clinical Investigation

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
This consensus highlights critical research gaps in obesity epidemiology, phenotypic heterogeneity and clinical management, calling for advanced methodologies, collaborative strategies and innovative policies to mitigate the global obesity epidemic and its socio‐economic impacts.
Federico Carbone   +28 more
wiley   +1 more source

Long-term safety, efficacy, and patient acceptability of the intrauterine Copper T-380A contraceptive device [PDF]

open access: yes, 2010
The intrauterine device (IUD), primarily in the form of the copper IUD, is used by more than 150 million women around the world, making it the most widely used reversible method of contraception.
Aeby, Tod, Kaneshiro, Bliss
core   +2 more sources

Cadherin‐6 controls neuronal migration during mouse neocortical development via an integrin‐mediated pathway

open access: yesThe FEBS Journal, EarlyView.
Neuronal migration plays essential roles in the establishment of mammalian brains, and its impairment causes severe developmental abnormalities and behavioral and cognitive deficits. Here, we report that cadherin‐6 (CDH6), an unusual cadherin molecule containing an RGD integrin‐binding motif in the first extracellular domain, controls the motility of ...
Yuki Hirota   +7 more
wiley   +1 more source

Milk and plasma pharmacokinetics of single‐dose ubrogepant in healthy lactating women

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The objectives of this study were to evaluate the safety, plasma and milk pharmacokinetics, excretion in breast milk, and the relative infant dose of ubrogepant following a single oral dose. Background Ubrogepant is a calcitonin gene‐related peptide receptor antagonist approved for the acute treatment of migraine in adults ...
Ramesh R. Boinpally   +3 more
wiley   +1 more source

Practice Nurse Provision of Long‐Acting Reversible Contraception: A Cross‐Sectional Survey of Knowledge and Practices

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To describe practice nurse long‐acting reversible contraception (LARC) knowledge and practices. Design Cross‐sectional survey. Methods Between July and December 2021, we conducted an online survey using convenience sampling to recruit Australian nurses who work in primary care, known as practice nurses. We collected data about demographics
Sharon James   +7 more
wiley   +1 more source

What are the Most Appropriate Treatments, Preventions and Family Planning Options for Patients with Factor V Leiden? [PDF]

open access: yes, 2020
The management of Venous Thromboembolism in terms of treatments and prevention has been well researched for patients who have been discovered as positive for Factor V Leiden genetic clotting disorder, in either the homozygous or the heterozygous genotype.
Wolf, Simha
core   +1 more source

Young‐onset type 2 diabetes—Epidemiology, pathophysiology, and management

open access: yesJournal of Diabetes Investigation, EarlyView.
The burden of young‐onset type 2 diabetes is increasing globally, disproportionately affecting non‐White ethnic groups and low‐ and middle‐income countries. Young‐onset type 2 is more heterogeneous regarding the genetic and environmental contributions to its underlying pathophysiology, which poses challenges for glycemic management.
Andrea O.Y. Luk   +5 more
wiley   +1 more source

Matrix and reservoir-type multipurpose vaginal rings for controlled release of dapivirine and levonorgestrel [PDF]

open access: yes, 2016
Blanda, Wendy   +10 more
core   +1 more source

Effects of gestational intermittent hypoxia on the respiratory system: A tale of the placenta, fetus, and developing offspring

open access: yesJournal of Sleep Research, EarlyView.
Effects of gestational intermittent hypoxia on maternal, fetal and offspring respiratory system. In black, effects in humans; in red, in vitro effects; in blue, effects in animal models. Summary Obstructive sleep apnea (OSA) is a common sleep disorder that is associated with a wide variety of health conditions, including cardiovascular, cerebrovascular,
Esther Valverde‐Pérez   +4 more
wiley   +1 more source

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