Results 61 to 70 of about 2,079,858 (263)
Nanomaterials, 2021 To investigate the potential of sorafenib (SF) in preoperative chemotherapy for cervical cancer to reduce tumor volume, sorafenib micelles (SF micelles) with good stability and high drug loading were designed.
Jun Wang +6 more
doaj +1 more source
Vaginal delivery of siRNA using a novel PEGylated lipoplex-entrapped alginate scaffold system [PDF]
, 2011 Sustained vaginal delivery of siRNA has been precluded by the mucosal barrier lining the vaginal tract. In contrast to prior reports, we showed that conventional lipoplexes administered intravaginally are unable to reach the vaginal epithelium under ...
Burgess, Melinda +3 more
core +1 more source
Acta Pharmaceutica Sinica B, 2017 Lack of mucoadhesive properties is the major drawback to poloxamer 407 (F127)-based in situ hydrogels for mucosal administration. The objective of the present study was to construct a novel mucoadhesive and thermosensitive in situ hydrogel drug delivery ...
Liqian Ci +5 more
doaj +1 more source
Recent Advances in Polymer-Based Vaginal Drug Delivery Systems
Pharmaceutics, 2021 The vagina has been considered a potential drug administration route for centuries. Most of the currently marketed and investigated vaginal formulations are composed with the use of natural or synthetic polymers having different functions in the product.
Tomasz Osmałek +10 more
doaj +1 more source
Journal of Pharmaceutical Analysis, 2017 Two simple and sensitive high performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) methods were developed and validated for the determination of fenticonazole in human plasma after percutaneous and intravaginal administration ...
Weixing Mao +5 more
doaj +1 more source
Application of Exogenous GnRH in Food Animal Production
Animals, 2023 Over several decades, exogenous GnRH and agonists have been employed for controlling reproductive cascades in animals, and treating some reproductive morbidities.
A. H. M. Musleh Uddin +4 more
doaj +1 more source
Preclinical Assessment of HIV Vaccines and Microbicides by Repeated Low-Dose Virus Challenges [PDF]
, 2005 BACKGROUND: Trials in macaque models play an essential role in the evaluation of biomedical interventions that aim to prevent HIV infection, such as vaccines, microbicides, and systemic chemoprophylaxis.
Feinberg, Mark B +3 more
core +5 more sources
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To evaluate the practicability of self‐collected tampons with the MPap assay for endometrial cancer (EC) detection, by comparing with the results of cervical swabs. Methods A total of 85 women at Tri‐Service General Hospital (TSGH) were included to directly compare the performance of physician‐collected swabs and self‐collected ...
Kuo‐Min Su +5 more
wiley +1 more source
Fertility in men with spinal cord injury [PDF]
, 2016 Young men comprise the overwhelming majority of men with spinal cord injury (SCI), the incidence of which has been growing over the years. Due to advances in physical medicine and rehabilitation, remarkable improvements in survival rates have been ...
Grgić, Franjo +5 more
core +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak +11 more
wiley +1 more source