Results 71 to 80 of about 2,079,858 (263)

The Benefit and Risk of Misoprostol Use: in Obstetrics and Gynecology [PDF]

open access: yes, 2015
Misoprostol is licensed to treat gastric ulcers but now it is widely used for a variety of indications in osbtetrics and gynecology. This is called ‘off-label' use. Misoprostol is cheap, stable at room temperature and easily to access it.
Desrini, S. (Sufi)
core   +2 more sources

Sulfonate-modified phenylboronic acid-rich nanoparticles as a novel mucoadhesive drug delivery system for vaginal administration of protein therapeutics: improved stability, mucin-dependent release and effective intravaginal placement

open access: goldInternational Journal of Nanomedicine, 2016
Effective interaction between mucoadhesive drug delivery systems and mucin is the basis of effective local placement of drugs to play its therapeutic role after mucosal administration including vaginal use, which especially requires prolonged drug ...
Chunyan Li   +7 more
openalex   +3 more sources

Forbs in Viking lands: the effect of disturbing dominant graminoids on recruitment in tundra grasslands

open access: yesOikos, EarlyView.
Grasslands, by definition, are dominated by graminoids. Nevertheless, forbs also make up a substantial part of vascular plant diversity in grasslands and are important resources of mammalian herbivores. However, forb recruitment is constrained by successful dominant graminoids, limiting access to safe sites for germination.
Gerardo Celis   +5 more
wiley   +1 more source

Vaginal Microbiota and Ovarian Cancer: A New Frontier in Immunomodulation and Diagnosis

open access: yesImmunology, EarlyView.
Microbial imbalance, dysbiosis, plays a role in ovarian carcinogenesis by interacting with the immune system and altering inflammatory pathways, notably Th17 pathways. In contrast, eubiosis, characterised by Lactobacillus dominance, protects against infections and maintains hormone metabolism.
Wafa Babay   +4 more
wiley   +1 more source

Development and characterization of long-acting darifenacin intravaginal ring for managing overactive bladder in women: harnessing QbD approach

open access: yesFuture Journal of Pharmaceutical Sciences
Background The oral administration of darifenacin hydrobromide (DBr) is associated with low bioavailability of 15–19% due to poor solubility and extensive first-pass metabolism.
Manisha Lalan   +3 more
doaj   +1 more source

Induced Abortion by Vaginal Use of Aluminum Phosphide in a 44-Year-Old Woman: A Case Report [PDF]

open access: yesInternational Journal of Medical Toxicology and Forensic Medicine, 2020
Aluminum phosphide (AlP) is an efficient and toxic pesticide that is easily available in many Asian countries such as Iran. Many cases of unintentional or suicidal use of AlP have been reported in these countries, and these statistics are rising rapidly.
Zahra Khalighi   +4 more
doaj   +1 more source

A Comparison of Synthetic Osmotic Dilators and Pharmacologic Agents for Cervical Ripening in Induction of Labor: A Systematic Review and Meta‐Analysis

open access: yesJournal of Midwifery &Women's Health, EarlyView.
Introduction Given the rising number of studies on synthetic osmotic dilators, there is a lack of comprehensive reviews for their use compared with other commonly used cervical ripening methods. This study aimed to examine the maternal and neonatal safety and efficacy in cervical ripening and labor induction using synthetic osmotic dilators compared ...
Gi Wook Ryu, Sun‐Young Park
wiley   +1 more source

Superovulation, in vivo Embryo Recovery and Cryopreservation for Aoudad (Ammotragus Lervia) Females Using Osmotic Pumps and Vitrification : A Preliminary Experience and its Implications for Conservation [PDF]

open access: yes, 2013
We thank all of the administrative, veterinary and animal keeper staff of the Leon Zoological Park and the embryologists (especially to Claudia Gonzalez) of the Instituto de Ciencias en Reproducción Humana, also to J.I Castillo-Quan for critical reading ...
de Barroso-Padilla, José Jesús   +5 more
core   +1 more source

Probiotic‐Based Materials as Living Therapeutics

open access: yesAdvanced Materials, Volume 38, Issue 1, 2 January 2026.
Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio   +2 more
wiley   +1 more source

Designer Solid Self‐Emulsifying Nanovaccines Enable Dual Modulation of Dendritic Cells and T Cells for Potent Antitumor Immunity

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
A solid self‐emulsifying (SSE) platform is loaded with peptide antigens and CpG to form the SSE vaccine. An ApoE‐enriched corona promotes dendritic cell internalization, enabling antigen presentation and T cell activation. Squalene from the SSE also sensitizes T cells by promoting lipid raft formation.
Xueying Shen   +8 more
wiley   +1 more source

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