Results 91 to 100 of about 74,108 (188)
Abstract Study Question To describe the blood product utilization during neonatal and pediatric extracorporeal membrane oxygenation (ECMO) and to determine whether its usage correlates with clinical outcomes of bleeding, thrombosis or mortality. Design Prospective observational study of neonatal and pediatric ECMO patients from September 2016, until ...
Rebecca Barton +15 more
wiley +1 more source
Intravascular Hemolysis of Red Blood Cells in the Development of Organ Dysfunctions in Critical Conditions [PDF]
The review analyzes the literature data, which suggest that microcirculatory bed disorders underlie organ dysfunctions in critical conditions, are largely associated with intravascular hemolysis of red blood cells, release of free hemoglobin and its ...
Yu. I. Orlov
core +1 more source
Abstract Background Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem cell disorder caused by somatic mutations in the PIGA gene, resulting in loss of glycosylphosphatidylinositol (GPI)‐anchored proteins, including the complement regulatory proteins, CD55 and CD59.
Ganesh Raman +4 more
wiley +1 more source
Microvascular stasis and hemolysis: coincidence or causality?
Katharina Effenberger-Neidnicht,1 Simon Bornmann,1 Johannes Jägers,2 Vivien Patyk,1 Michael Kirsch11Institute of Physiological Chemistry, University Hospital Essen, Essen, Germany; 2Institute of Physiology, University Hospital Essen, Essen ...
Effenberger-Neidnicht K +4 more
core
BACKGROUND Platelet transfusion is a common clinical practice required for therapeutic purposes in the setting of symptomatic thrombocytopenia, and, in some cases, prophylactically for asymptomatic thrombocytopenia.
Fletcher, Craig H +2 more
core +1 more source
Abstract Objective To evaluate intraoperative cholangiography (IOC) during open cholecystectomy in dogs with benign gallbladder disease, including cases with preoperative common bile duct (CBD) obstruction, and to describe the short‐term outcomes. Study design Retrospective case series. Animals A total of 73 client‐owned dogs.
Ryusei Konno +7 more
wiley +1 more source
Paroxysmal nocturnal hemoglobinuria masquerading as hemolytic uremic syndrome: a Case Report
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired disorder of intravascular hemolysis caused by a somatic mutation in the gene responsible for glycosylphosphatidylinositol (GPI)-anchored complement regulatory proteins.
Menghan Gao +3 more
doaj +1 more source
Summary Precursor‐targeted immune‐mediated anaemia (PIMA) is an increasingly recognised cause of nonregenerative anaemia in dogs and may be difficult to distinguish from infectious or other immune‐mediated conditions. This report describes a dog presenting severe nonregenerative anaemia, leukopenia and thrombocytopenia, initially testing seroreactive ...
Vinícius dos Santos Resende Rodrigues +5 more
wiley +1 more source
Targeted deletion of the CD59 gene causes spontaneous intravascular hemolysis and hemoglobinuria
The glycolipid-anchored glycoprotein CD59 inhibits assembly of the lytic membrane attack complex of complement by incorporation into the forming complex.
Hanna, S. M. +5 more
core +1 more source
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley +1 more source

