Results 11 to 20 of about 2,124,955 (409)

European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke

open access: yesEuropean Stroke Journal, 2021
Intravenous thrombolysis is the only approved systemic reperfusion treatment for patients with acute ischaemic stroke. These European Stroke Organisation (ESO) guidelines provide evidence-based recommendations to assist physicians in their clinical ...
E. Berge   +9 more
semanticscholar   +1 more source

Effect of Mechanical Thrombectomy Without vs With Intravenous Thrombolysis on Functional Outcome Among Patients With Acute Ischemic Stroke: The SKIP Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2021
Importance Whether intravenous thrombolysis is needed in combination with mechanical thrombectomy in patients with acute large vessel occlusion stroke is unclear.
Kentaro Suzuki   +29 more
semanticscholar   +1 more source

Effect of Endovascular Treatment Alone vs Intravenous Alteplase Plus Endovascular Treatment on Functional Independence in Patients With Acute Ischemic Stroke: The DEVT Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2021
Importance For patients with large vessel occlusion strokes, it is unknown whether endovascular treatment alone compared with intravenous thrombolysis plus endovascular treatment (standard treatment) can achieve similar functional outcomes.
W. Zi   +52 more
semanticscholar   +1 more source

A Randomized Trial of Intravenous Alteplase before Endovascular Treatment for Stroke.

open access: yesNew England Journal of Medicine, 2021
BACKGROUND The value of administering intravenous alteplase before endovascular treatment (EVT) for acute ischemic stroke has not been studied extensively, particularly in non-Asian populations.
N. LeCouffe   +64 more
semanticscholar   +1 more source

Restriction of Intravenous Fluid in ICU Patients with Septic Shock.

open access: yesNew England Journal of Medicine, 2022
BACKGROUND Intravenous fluids are recommended for the treatment of patients who are in septic shock, but higher fluid volumes have been associated with harm in patients who are in the intensive care unit (ICU). METHODS In this international, randomized
T. Meyhoff   +67 more
semanticscholar   +1 more source

Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke.

open access: yesNew England Journal of Medicine, 2020
BACKGROUND In acute ischemic stroke, there is uncertainty regarding the benefit and risk of administering intravenous alteplase before endovascular thrombectomy.
Pengfei Yang   +58 more
semanticscholar   +1 more source

Use of Intravenous Iodinated Contrast Media in Patients with Kidney Disease: Consensus Statements from the American College of Radiology and the National Kidney Foundation.

open access: yesRadiology, 2020
Intravenous iodinated contrast media are commonly used with CT to evaluate disease and to determine treatment response. The risk of acute kidney injury (AKI) developing in patients with reduced kidney function following exposure to intravenous iodinated ...
M. Davenport   +8 more
semanticscholar   +1 more source

Cocaine self-administration in the mouse: A low-cost, chronic catheter preparation [PDF]

open access: yes, 2012
Intravenous drug self-administration is the most valid animal model of human addiction because it allows volitional titration of the drug in the blood based on an individual’s motivational state together with the pharmacokinetic properties of the ...
Brian Cadle   +4 more
core   +3 more sources

Magnesium sulphate in the treatment of acute asthma: evaluation of current practice in adult emergency departments [PDF]

open access: yes, 2009
Background: A recent meta-analysis showed that intravenous and nebulised magnesium sulphate have similar levels of evidence to support their use in the treatment of acute asthma in adults. This consisted of weak evidence of effect on respiratory function
Goodacre, S., Jones, L.A.
core   +1 more source

Outcomes after angiography with sodium bicarbonate and acetylcysteine [PDF]

open access: yes, 2018
Background: Intravenous sodium bicarbonate and oral acetylcysteine are widely used to prevent acute kidney injury and associated adverse outcomes after angiography without definitive evidence of their efficacy.
,   +19 more
core   +1 more source

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