Results 331 to 340 of about 2,124,955 (409)

Successful Management of Refractory Pulmonary Mucormycosis Using Intracavitary Amphotericin B: A Case Report and Literature Review. [PDF]

Am J Case Rep
Gao Y, Wang H, Bai XF, Wu Y, Li X, Wang M, Kanani F.   +6 more
europepmc   +1 more source

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

Advanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou, Yuqing Lv, Lin Li, Shukui Zhang, Jiaqi Liang, Chengchao Wu, Enyu Huang, Jianwei Jiao, Jingjing Zhang   +8 more
wiley   +1 more source

A retrospective cohort study on the use of ultrasound in establishing peripheral intravenous access in emergency patients with difficult veins. [PDF]

Medicine (Baltimore)
Yuan M, Liu Y, Tang L, Zhang W.
europepmc   +1 more source

Pharmacokinetics of FK 506: Preclinical and clinical studies [PDF]

, 1990
Cadoff, E, Fung, JJ, Imventarza, O, Iwasaki, K, Jain, A, Krajack, A, Nagase, K, Starzl, TE, Todo, S, Venkataramanan, R, Warty, V   +10 more
core  

Discovery of a Potent and Selective TEAD Degrader with Durable Degradation Activity

Advanced Science, EarlyView.
KG‐FP‐003, a highly potent TEAD‐YAP PROTAC derived from the patented inhibitor is developed. It selectively degrades endogenous TEAD proteins in HiBiT systems without IMiD‐related off‐target effects. Screening across 867 cancer cell lines revealed broad and superior anti‐tumor activity, highlighting its therapeutic potential through targeted TEAD ...
Linhui Cao, Jing Yang, Yuhang Liu, Xiaotong Chen, Yufang Shi, Yunshuo Zhao, Yong Zhang, Jian Chen, Bowen Li, Wuqiang Wen, Lu Chen, Bo Peng, Lu Huang, Yanli Sun, Lixin Zhou, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Zhixiang Guo, Jing Xing, Guangya Zhu, Yazhou Wang, Baishan Jiang, Jing Lu, Kehao Zhao, Wenchao Lu   +25 more
wiley   +1 more source

Salmonella-associated endophthalmitis in healthy infants: Two case reports and a review of the literature. [PDF]

Am J Ophthalmol Case Rep
Alhejaili A, Alsaif A, Madani F, Althaqib RN, Semidey V, Babgi R, Alsulaiman HM.   +6 more
europepmc   +1 more source

Activation of the coagulation cascade as a mechanism for selective nanoparticle-mediated RNA delivery to the endothelium in vivo. [PDF]

Sci Adv
Guzman EB, Kowalski PS, Langer RS, Anderson DG.   +3 more
europepmc   +1 more source

The role of β-lactam/β-lactamase inhibitor combinations in multidrug-resistant bacterial infections: a comprehensive meta-analysis. [PDF]

Am J Transl Res
Wu F, Liu Q, Hu P, Wu C.
europepmc   +1 more source

Intra-articular Migration of a Broken Needle in an Intravenous Drug User: A Case Report and Surgical Management. [PDF]

Cureus
Kaushik R, Singh T, Kumar D, Aggarwal L, Mir MA.   +4 more
europepmc   +1 more source

Emphysematous pyelonephritis in a diabetic child: a case report and review of the literature. [PDF]

J Med Case Rep
Bazargani B, Moghtaderi M, Esfandiary H, Ghanbarian F, Samieefar N.   +4 more
europepmc   +1 more source