Results 61 to 70 of about 2,458,308 (203)

Monitoring of fibrinolytic system activity with plasminogen, D-dimers and FDP in primary total knee arthroplasty (TKA) after topical, intravenous or combined administration of tranexamic acid

Biomedical Papers, 2020
Aim: We assessed various ways of tranexamic acid (TXA) administration on the fibrinolytic system. Blood loss, transfusions, drainage and haematoma were secondary outcomes.
Jiri Lostak, Jiri Gallo, Ludek Slavik, Jana Zapletalova, Lubos Balaz   +4 more
doaj   +1 more source

Inhalation treatment of lung cancer: the influence of composition, size and shape of nanocarriers on their lung accumulation and retention

Cancer Biology & Medicine, 2014
Objective Various nanoparticles have been designed and tested in order to select optimal carriers for the inhalation delivery of anticancer drugs to the lungs.
Olga B. Garbuzenko, Gediminas Mainelis, Oleh Taratula, Tamara Minko   +3 more
doaj   +1 more source

Intravenous voriconazole after toxic oral administration

, 2010
In a male patient with rhinocerebral invasive aspergillosis, prolonged high-dosage oral administration of voriconazole led to hepatotoxicity combined with a severe cutaneous reaction while intravenous administration in the same patient did not.
Van Assen, S., Alffenaar, J.W.C., Kosterink, J.G.W., Van Der Werf, T.S., Kosterink, J.G.W.; id_orcid, Uges, D.R.A., De Monchy, J.G.R.   +6 more
core   +1 more source

Time associated with intravenous zoledronic acid administration in patients with breast or prostate cancer and bone metastasis

, 2012
Akshara Richhariya1, Yi Qian2, Yufan Zhao2, Karen Chung11Amgen Inc, Global Health Economics, Thousand Oaks, CA, USA; 2Amgen Inc, Global Biostatistical Sciences, Thousand Oaks, CA, USAPurpose: Intravenous (IV) zoledronic acid (ZA) is commonly used to ...
Richhariya A, Qian Y, Chung K, Zhao Y
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Adverse events in different administration routes of Edaravone: A pharmacovigilance study based on the FDA adverse event reporting system.

PLoS ONE
The U.S. Food and Drug Administration (FDA) approved intravenous edaravone for the treatment of amyotrophic lateral sclerosis (ALS) in 2017, followed by the approval of the oral formulation in 2022.
Deye Ge, Liyan Wu, Jingrong Yang, Jingxian Sun, Jinying Wang, Jingxin Wang, Huihui Song, Ran Wei, Zecheng Xu, Binbin Zhao, Rongfei Sun, Yifei Wang   +11 more
doaj   +1 more source

Prevalence of intravenous medication administration errors: a cross-sectional study

, 2017
Tezeta Fekadu,1 Mebrahtu Teweldemedhin,2 Eyerusalem Esrael,1 Solomon Weldegebreal Asgedom1 1School of Pharmacy, Department of Clinical Pharmacy, College of Health Sciences, Mekelle University, Mekelle, 2Unit of Biomedical Science, School of Medicine ...
Teweldemedhin M, Esrael E, Asgedom SW, Fekadu T   +3 more
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The effect of excipients on pharmacokinetic parameters of parenteral drugs [PDF]

, 2005
In the pharmaceutical industry, the main goal of early phase in vivo studies is to assess pharmacokinetic properties of a compound in laboratory animals. These data provide a basis for selecting and optimizing drug candidates.
Egger-Heigold, Barbara
core   +1 more source

Harnessing synaptic vesicle release and recycling with antibody shuttle for targeted delivery of therapeutics to neurons

Molecular Therapy: Methods & Clinical Development
The effective delivery of therapeutic molecules to neurons are mainly limited by the presence of the blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB), leading to suboptimal therapeutic outcomes in neurodegenerative diseases treatment.
Karen Kar Lye Yee, Junichi Kumamoto, Daijiro Inomata, Naoki Suzuki, Ryuhei Harada, Norihiro Yumoto   +5 more
doaj   +1 more source

Ultrasound evaluation of peripheral intravenous catheter thrombus formation associated with intravenous flucloxacillin administration: A prospective observational pilot study

Purpose The purpose of this study was to sonographically evaluate whether intravenous (IV) flucloxacillin administration was associated with an increased risk of peripheral intravenous catheter (PIVC) thrombus formation. Methods This observational study
Keijzers, Gerben, Snelling, Peter J, Nightingale, Rachael, Bulmer, Andrew C, Hewage, Wenu   +4 more
core   +1 more source

Long-term intravenous administration of carboxylated single-walled carbon nanotubes induces persistent accumulation in the lungs and pulmonary fibrosis via the nuclear factor-kappa B pathway

, 2016
Yue Qin,1,* Suning Li,2,* Gan Zhao,2,* Xuanhao Fu,1 Xueping Xie,1 Yiyi Huang,1 Xiaojing Cheng,3 Jinbin Wei,1 Huagang Liu,1 Zefeng Lai1 1Pharmaceutical College, Guangxi Medical University, 2Department of Pharmacy, The Maternal and Child Health Hospital ...
Liu H, Lai Z, Li S, Huang Y, Xie X, Fu X, Zhao G, Qin Y, Wei J, Cheng X   +9 more
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