Results 241 to 250 of about 1,116,406 (351)

PDZK1 Protects Against RPE Senescence by Targeting the 14‐3‐3ε‐mTOR Axis to Attenuate Early Diabetic Retinopathy

Advanced Science, EarlyView.
PDZK1 down‐regulation couples high‐glucose stress to RPE senescence via a PDZK1–14‐3‐3ε–mTOR axis. Restoring PDZK1 or clearing senescent cells rescues retinal homeostasis and mitigates early diabetic retinopathy (DR). This study provides direct evidence linking RPE cell senescence to DR pathogenesis and reveals a promising therapeutic strategy for DR ...
Jian Zhao, Junbiao Zhang, Yanli Liu, Lili Wang, Chunxi Huang, Wei Chi, Meixia An   +6 more
wiley   +1 more source

Pain and immune function in patients undergoing gastric cancer surgery following stellate ganglion block with total intravenous anesthesia. [PDF]

World J Gastrointest Surg
Wu Z, Cai HQ, Wang CF, Yu XY, Wang JQ.
europepmc   +1 more source

A Single‐Molecule Pleuripotent Scaffold for Combinational Therapy of Alzheimer's Disease via Intranasal Administration

Advanced Science, EarlyView.
Herein, guanidinium‐modified calix[5]arene (GC5AY) is developed featuring small size, positive charge, and desirable amphiphilicity, that can efficiently traverse the nasal mucosal barrier for brain drug delivery. Additionally, possessing inherent therapeutic functions, GC5AY can thus serve as a single‐molecule pleuripotent scaffold for multi‐target ...
Jian‐Mei Gao, Wen‐Bo Li, Na‐Na Chen, Yang Yi, Ze‐Han Wang, Xian Chen, Yang‐Yang Zhao, Ze‐Li Yuan, Jie Gao, Yu‐Chen Pan, Dong‐Sheng Guo, Qi‐Hai Gong   +11 more
wiley   +1 more source

Benefit of Gastro™ Laryngeal Mask Airway® during Total Intravenous Anesthesia for Endoscopic Retrograde Cholangiopancreatography: A Randomized Controlled Study.

Ann Afr Med
Archana KN, Subramanian A, Kumar PH, Kumararadhya GB, Nandeesh HP, Shivakumar KG.   +5 more
europepmc   +1 more source

Total intravenous anesthesia using midazolam and dexmedetomidine as substitutes for propofol in a pediatric patient with egg allergy and a family history of malignant hyperthermia. [PDF]

Saudi J Anaesth
Inoue M, Morita M.
europepmc   +1 more source

The Use of 0.25% Lidocaine with Fentanyl and Pancuronium for Intravenous Regional Anesthesia

, 1997
F. Sztark, M. Thicoïpé, J. F. Favarel-Garrigues, P. Lassié, M. E. Petitjean, P. Dabadie   +5 more
openalex   +1 more source

Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis

Advanced Science, EarlyView.
The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang, Di Mu, Su Liu, Peng‐Bo Jing, Bin Wu, Xiao‐Mei Yang, Jia‐Yi Ge, Qing‐Yi Li, Hao‐Hao Chen, Feng‐Ming Zhang, Bing Wang, Ying‐Ying Zhang, Linnan Qian, Zi‐Yi Zhu, Yu‐Sen Ou, Shi‐Yu Sun, Lin Luo, Yu Feng, Changyu Jiang, Zhuo Sun, Yong Chen, Hai‐Li Pan, Bin Wang, Fen‐Fei Gao, Jie Wu, Zhigang Lu, Tong Liu, Yan‐Gang Sun, Xing‐Jun Liu   +28 more
wiley   +1 more source

Total Intravenous Anesthesia Using Remimazolam for Transcarotid Approach Transcatheter Aortic Valve Replacement: A Case Report. [PDF]

Cureus
Kitaura A, Sakamoto H, Tsukimoto S, Yuasa H, Nakajima Y.   +4 more
europepmc   +1 more source

Efficacy of Sequential Hepatic Vein Embolization Following Portal Vein Embolization in Promoting Regeneration of Liver Volume and Function Before Right‐Sided Major Hepatectomy

Annals of Gastroenterological Surgery, EarlyView.
Sequential hepatic vein embolization (HVE) following portal vein embolization (PVE) significantly improves both the volume and function of the future remnant liver (FRL) compared to PVE alone. In this study, the FRL regeneration rates for volume and function were markedly higher and faster in the PVE–HVE group, with no differences in surgical outcomes ...
Thanh Tung Lai, Kosuke Matsui, Hideyuki Matsushima, Hidekazu Yamamoto, Gozo Kiguchi, Hisashi Kosaka, Van Khanh Nguyen, Yasuhiro Ueno, Shuji Kariya, Masaki Kaibori   +9 more
wiley   +1 more source