This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin +14 more
wiley +1 more source
The anesthetist's choice of inhalational vs. intravenous anesthetics has no impact on survival of glioblastoma patients. [PDF]
Schmoch T +10 more
europepmc +1 more source
Intravenous Lidocaine Alleviates the Pain of Propofol Injection by Local Anesthetic and Central Analgesic Effects [PDF]
Jibin Xing +5 more
openalex +1 more source
Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites. [PDF]
Voltage-gated sodium (NaV) channels are important targets of general anesthetics, including the intravenous anesthetic propofol. Electrophysiology studies on the prokaryotic NaV channel NaChBac have demonstrated that propofol promotes channel activation ...
Bondarenko, Vasyl +12 more
core +1 more source
Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo +3 more
wiley +1 more source
Dexmedetomidine Associated with Intraoperative Floppy Iris Syndrome in Ophthalmic Surgery [PDF]
Inci Dersu
doaj +1 more source
BackgroundPatients diagnosed with stage III breast cancer often undergo surgery, radiation therapy, and chemotherapy as part of their treatment. The choice of anesthesia technique during surgery has been a subject of interest due to its potential ...
Emily Tzu-Jung Kuo +2 more
doaj +1 more source
Inhalational versus intravenous anesthetics during one lung ventilation in elective thoracic surgeries: A narrative review. [PDF]
Parab S, Gaikwad S, Majeti S.
europepmc +1 more source
Effects of intravenous anesthetic agents on middle cerebral artery blood flow velocity during induction of general anesthesia [PDF]
Achim Thiel +3 more
openalex +1 more source
Mechanisms and Efficacy of Intravenous Lipid Emulsion Treatment for Systemic Toxicity From Local Anesthetics [PDF]
Yang Liu +4 more
openalex +1 more source

