Results 101 to 110 of about 43,030 (312)

Silencing Myostatin Using In Vivo Self‐Assembled siRNA Protects Against Cancer‐ and Dexamethasone‐Induced Muscle Atrophy

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin   +14 more
wiley   +1 more source

The anesthetist's choice of inhalational vs. intravenous anesthetics has no impact on survival of glioblastoma patients. [PDF]

open access: yesNeurosurg Rev, 2021
Schmoch T   +10 more
europepmc   +1 more source

Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites. [PDF]

open access: yes, 2018
Voltage-gated sodium (NaV) channels are important targets of general anesthetics, including the intravenous anesthetic propofol. Electrophysiology studies on the prokaryotic NaV channel NaChBac have demonstrated that propofol promotes channel activation ...
Bondarenko, Vasyl   +12 more
core   +1 more source

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo   +3 more
wiley   +1 more source

Dexmedetomidine Associated with Intraoperative Floppy Iris Syndrome in Ophthalmic Surgery [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Inci Dersu
doaj   +1 more source

Inhaled anesthesia associated with reduced mortality in patients with stage III breast cancer: A population-based study.

open access: yesPLoS ONE
BackgroundPatients diagnosed with stage III breast cancer often undergo surgery, radiation therapy, and chemotherapy as part of their treatment. The choice of anesthesia technique during surgery has been a subject of interest due to its potential ...
Emily Tzu-Jung Kuo   +2 more
doaj   +1 more source

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