Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine
Advanced Materials, EarlyView.A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen +5 more
wiley +1 more source
COMPARATIVE EFFECTS OF INHALATION VERSUS INTRAVENOUS ANESTHETIC DRUGS ON RENAL MODYNAMICS DURING HEMORRHAGIC HYPOVOLEMIA [PDF]
, 1982 LAWRENCE L. PRIANO
openalex +1 more source
Microbubble Shell Stiffness Engineering Enhances Ultrasound Imaging, Drug Delivery, and Sonoporation
Advanced Materials, EarlyView.Shell‐engineered poly(alkyl cyanoacrylate) microbubbles with tunable stiffness improve ultrasound imaging and therapy. Adjusting the length of the alkyl chain and the glass transition temperature maintains a narrow microbubble size distribution while enhancing drug loading, sonoporation and the acoustic response.
Roman A. Barmin +30 more
wiley +1 more source
Peptide Amphiphiles Hitchhike on Endogenous Biomolecules for Enhanced Cancer Imaging and Therapy
Advanced Materials, EarlyView.Weakly assembled peptide amphiphile nanostructures disassemble in circulation and reassemble with blood biomolecules, mainly lipoproteins. Binding to blood biomolecules prolongs blood circulation and improves accumulation in solid tumors. In the tumor microenvironment, peptide amphiphiles assemble with cholesterol‐rich domains of cell membranes ...
Li Xiang +19 more
wiley +1 more source
Proper Use of Ketamine and Innovar [PDF]
, 1972 Definitions of ketamine and innovar along with corresponding indications, contraindications, techniques for administration, complications, and treatment of ...
Corssen, Guenter
core +1 more source
Optoacoustic‐Guided Magnetic Microrobot Platform for Precision Drug Delivery
Advanced Materials, EarlyView.Optoacoustically guided FePt@ZIF‐8‐based microrobots are designed with high drug loading capacity, controllable locomotion, and deep‐tissue imaging capability. By integrating navigation, drug release, and real‐time monitoring into a single platform, they provide a versatile tool for precise intervention, opening new possibilities for treating ...
Fan Wang +12 more
wiley +1 more source
What have we learned from two-pore potassium channels? Their molecular configuration and function in the human heart [PDF]
, 2012 Two-pore domain potassium channels (K2P) control excitability, stabilize the resting membrane potential below firing threshold, and accelerate repolarisation in different cells.
Benyhe, Sándor +11 more
core
Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity
Advanced Science, EarlyView.This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong +16 more
wiley +1 more source
AnaConDa Device: Solution to Perform Cardiac Surgery Without Intravenous Anesthetic During the Corona Virus Disease 2019 Pandemic [PDF]
, 2020 François Labaste +5 more
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ATF5‐Dependent GDF15 Expression Mediates Anesthesia‐Induced Neuroprotection Against Stroke
Advanced Science, EarlyView.Anesthesia‐induced preconditioning protects against perioperative stroke. By manipulating ATF5 in excitatory neurons, it is shown that anesthesia‐driven ATF5 upregulation activates the mitochondrial unfolded protein response (UPRmt) and elevates GDF15 expression.
Xianshu Ju +11 more
wiley +1 more source