A galvanic replacement is used to control dual atomic metals (Au and Ir) on a covalent organic framework (COF) nanoparticle and then coated with hyaluronic acid (HA). Under a specific bimetallic ratio (COF/Aux/Ir1‐x), the optimization can be achieved for the conversion of intracellular nutrients into reactive species (HOCl and O2• ─) and effectively ...
Wei‐Chung Pan+9 more
wiley +1 more source
Anesthetic and analgesic management of a skunk (Mephitis mephitis) undergoing a laminectomy for cauda equina compression [PDF]
A 6-year-old, male striped skunk (Mephitis mephitis) weighing 5.9 kg was anesthetized for diagnostic imaging procedures and subsequently for a laminectomy at level L6/S1 as treatment of lumbosacral stenosis. On both occasions, anesthesia was induced by a
Gozalo Marcilla, Miguel+5 more
core
Anesthetic, cardiorespiratory, and metabolic effects of four intravenous anesthetic regimens induced in horses immediately after maximal exercise [PDF]
John A. E. Hubbell+5 more
openalex +1 more source
Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim+12 more
wiley +1 more source
Room G, 10/17/2000 2: 00 PM - 4: 00 PM (PS) Intravenous Anesthetics Inhibit Capacitative Calcium Entry in Pulmonary Artery Smooth Muscle Cells [PDF]
Izumi Kondo+3 more
openalex +1 more source
A high‐strength pH‐responsive hydrogel‐forming microneedle integrates gradient solvent replacement to enhance the mechanical properties of the acrylonitrile‐acrylic acid copolymer network, ensuring robust transdermal penetration and long‐term drug release.
Hui Li+12 more
wiley +1 more source
What have we learned from two-pore potassium channels? Their molecular configuration and function in the human heart [PDF]
Two-pore domain potassium channels (K2P) control excitability, stabilize the resting membrane potential below firing threshold, and accelerate repolarisation in different cells.
Benyhe, Sándor+11 more
core
Type I Interferon Signaling Augments Autoimmunity in Neuromyelitis Optica Spectrum Disorder
The cGAS‐STING innate immune pathway is excessively activated both in peripheral monocytes and CNS microglia in patients with NMOSD, leading to an overproduction of IFN‐I. IFN‐I subsequently acts on AQP4‐specific autoreactive T cells. Blocking this pathway may offer novel therapeutic options for individuals with NMOSD.
Tian‐Xiang Zhang+13 more
wiley +1 more source
Sevoflurane and desflurane protect cholinergic-induced bronchoconstriction of hyperreactive airways in rabbits [PDF]
Purpose: The potential of desflurane to alter respiratory mechanics in the presence of bronchial hyperresponsiveness (BHR) is still a subject of debate.
Boda, Krisztina+5 more
core
Changes in Bispectral Index during Coinduction with Intravenous Anesthetics Using Synergistic Interaction [PDF]
Ho Yeong Kil+4 more
openalex +1 more source