Various regional anesthetics have been used for postoperative analgesia for pediatric craniotomy. In this case series, we report retrospectively collected data on postoperative pain and analgesic use in 44 patients who received ultrasound-guided ...
Jordan I. Gaelen+6 more
doaj +1 more source
Designing the ideal perioperative pain management plan starts with multimodal analgesia. [PDF]
Multimodal analgesia is defined as the use of more than one pharmacological class of analgesic medication targeting different receptors along the pain pathway with the goal of improving analgesia while reducing individual class-related side effects ...
Mariano, Edward R., Schwenk, Eric S.
core +1 more source
Propofol Induction Reduces the Capacity for Neural Information Integration: Implications for the Mechanism of Consciousness and General Anesthesia [PDF]
The cognitive unbinding paradigm suggests that the synthesis of cognitive information is attenuated by general anesthesia. Here, we investigated the functional organization of brain activities in the conscious and anesthetized states, based on ...
Byung-Moon Choi+4 more
core +2 more sources
Ketamine-Medetomidine General Anesthesia Occurs With Alternation of Cortical Electrophysiological Activity Between High and Low Complex States [PDF]
Anesthetic agents are known to induce a range of alterations in cortical electrophysiological activity, such as the rise of signature patterns, changes in statistical properties, and altered dynamic behavior of neural records. Plenty of methods can be used to monitor these changes, among them complexity metrics demonstrated to have the power to ...
arxiv
Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee+6 more
wiley +1 more source
JUSTIFICATIVA E OBJETIVOS: Alguns estudos têm demonstrado que o uso do propofol é, algumas vezes, associado a bradiarritmias ou reversão de arritmias para ritmo sinusal.
Paulo Warpechowski+3 more
doaj +1 more source
Concerns of the anesthesiologist: anesthetic induction in severe sepsis or septic shock patients [PDF]
Septic patients portray instable hemodynamic states because of hypotension or cardiomyopathy, caused by vasodilation, thus, impairing global tissue perfusion and oxygenation threatening functions of critical organs.
Seok Hwa Yoon
doaj +1 more source
Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites. [PDF]
Voltage-gated sodium (NaV) channels are important targets of general anesthetics, including the intravenous anesthetic propofol. Electrophysiology studies on the prokaryotic NaV channel NaChBac have demonstrated that propofol promotes channel activation ...
Bondarenko, Vasyl+12 more
core +1 more source
Intravenous lipid infusion in toxicological practice [PDF]
The use of intravenous lipid emulsions (ILEs) is a relatively new method of treatment in toxicology. Initially, it was applied to control the resistant to other therapeutic methods systemic toxicity of local anesthetics.
Dimitrova, Simeonka+5 more
core +2 more sources
SYSTEMIC TOXICITY REACTIONS DUE TO EPIDURAL CATHETER DISPLACEMENT [PDF]
"nToxic reactions to local anesthetics may occur due to over dose, accidental intravenous injections or rapid systemic uptake of the drugs. But there have been few reports on toxicity due to displacement of epidural catheters after an initial ...
M H Ghafari+3 more
doaj +2 more sources