Results 91 to 100 of about 407,552 (296)

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Intravenous Immunoglobulin and its Complications

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2011
Intravenous immunoglobulin (IVIG) is a safe biological product used in many cases, such as primary and secondary immune deficiency, infectious diseases, critically ill patients and autoimmune disorders.
I Mohammadzadeh
doaj  

Advantage of the subcutaneous immunoglobulin replacement therapy in primary immunodeficient patients with or without secondary protein loss

The Turkish Journal of Pediatrics, 2018
In recent years subcutaneous immunoglobulin is widely used for primary immunodeficient patients. Subcutaneous administration provides a more stable and higher serum immunoglobulin levels due to continuous and steady transition from lymphatics to the ...
Pınar Gür-Çetinkaya, Deniz Nazire Çağdaş-Ayvaz, Ayça Burcu Öksüz, Ayşe Ertoy, Umut Hayran, Feride Özkan, Meliha Erol, İlhan Tezcan   +7 more
doaj   +1 more source

Self-reactivity in the dimeric intravenous immunoglobulin fraction

, 2007
Therapeutic intravenous immunoglobulin (IVIg) preparations contain antibodies reflecting the cumulative antigen experience of the donor population. IVIg contains variable amounts of monomeric and dimeric IgG, but there is little information available on ...
Stadler, Beda M, Bolli, Reinhard, SANDRA WYMANN, BEDA M. STADLER, ALEXANDER SCHAUB, ZSUZSANNE BELEZNAY, Wymann, Sandra, Ghielmetti, Marco, Heller, Manfred, Schaub, Alexander, Beleznay, Zsuzsanne, SYLVIA MIESCHER, Miescher, Sylvia, MANFRED HELLER, MARCO GHIELMETTI, REINHARD BOLLI   +15 more
core   +1 more source

Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations

Advanced Science, EarlyView.
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford, Matthew Tamasi, Elena Di Mare, Adam J. Gormley   +3 more
wiley   +1 more source

Adverse reactions of intravenous immunoglobulin

Saudi Medical Journal, 2000
OBJECTIVE: To study the frequency, type, and severity of adverse reactions to intravenous immunoglobulin infusions and possible preventable measures. METHODS: We prospectively studied the frequency, type, and severity of adverse reactions in 104 intravenous immunoglobulin infusions (IntraglobinTMF) given to 13 patients suffering from several ...
A M, Al-Wahadneh, I A, Khriesat, E H, Kuda   +2 more
openaire   +2 more sources

Fetal alloimmune thrombocytopenia and maternal intravenous immunoglobulin infusion [PDF]

, 2010
Different therapeutic approaches have been used in fetal-neonatal alloimmune thrombocytopenia, but many centers administer immunoglobulin G infusions to the pregnant woman.
Riethmacher, Regina, Tutschek, Boris, H. Lorenz, Wenzel, Folker, Stockschläder, Markus, R. Riethmacher, F. Wenzel, B. Tutschek, M. Stockschlader, Giers, Günther, Lorenz, Horst, G. Giers   +11 more
core   +1 more source

Dual Blockade of LILRB1 and LILRB2 Enhances Antiviral Immune Responses in SIV Infection

Advanced Science, EarlyView.
Dual LILRB1/B2 blockade with mac20G10 reshapes myeloid activation during acute SIV infection by targeting LILRB1 and LILRB2 on myeloid cells. This treatment enhances CD80 expression on selected myeloid subsets and increases plasma IFN‐λ, IL‐8, and IL‐1RA.
Florian Meurisse, Sixtine Coindre, Anne Wijkhuisen, Romain Marlin, Laure Fournier Le Ray, Juliette Pons, Melyssa Yaugel‐Novoa, Véronique Avettand‐Fenoel, Laurent Abi‐Rached, Anne‐Sophie Gallouet, Francis Relouzat, Mael Gourves, Asier Saez‐Cirion, Hisashi Arase, Gerard Zurawski, Sandra Zurawski, Nathalie Dereuddre‐Bosquet, Roger Le Grand, Stéphanie Simon, Olivier Lambotte, Benoit Favier   +20 more
wiley   +1 more source

Does the Use of Intravenous Immunoglobulin Improve Clinical Outcomes in Adults With Autoimmune Encephalitis? A Systematic Review

Brain and Behavior
Background Autoimmune encephalitis is an immune‐mediated inflammatory condition affecting the central nervous system. Current best‐practice guidelines recommend intravenous immunoglobulin (IVIG) for use if corticosteroids are ineffective, but the ...
Anahat Kalra, Olivia Mackay, Emma Thomas‐Jones, Tom Solomon, Paula Foscarini‐Craggs   +4 more
doaj   +1 more source