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The Medical Treatment of Epilepsy, 2020
K. Van Rijckevorsel-Harmant, M. Delire
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K. Van Rijckevorsel-Harmant, M. Delire
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Therapeutic intravenous immunoglobulins
Molecular Immunology, 2005Intravenous immunoglobulins (IVIg) are concentrated formulations of human IgG prepared by industrial fractionation of large pools of individual plasma donations. IVIg were developed 20 years ago for the prophylaxis support of immunodeficient patients.
Réal, Lemieux +2 more
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Clinical Immunology and Immunopathology, 1986
The development of immunoglobulin preparations suitable for intravenous use that are safe, acceptable, and efficacious represents a major advance in the treatment of immunodeficient patients. Experience in the United States and elsewhere in the world indicates that the benefits of use in patients with well-documented humoral immunodeficiency far ...
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The development of immunoglobulin preparations suitable for intravenous use that are safe, acceptable, and efficacious represents a major advance in the treatment of immunodeficient patients. Experience in the United States and elsewhere in the world indicates that the benefits of use in patients with well-documented humoral immunodeficiency far ...
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Safety of Intravenous Immunoglobulin
Archives of Neurology, 1993The current position of intravenous immunoglobulin (IVIG) in neurology is similar to that of plasmapheresis 10 years ago. Therapeutic claims have been made for an increasing number of neurologic disorders, based on small, uncontrolled studies. With the recent publication of a controlled trial of IVIG treatment in Guillain-Barre syndrome, 1 and trials ...
C A, Thornton, M, Ballow
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Human intravenous immunoglobulin therapy
Seminars in Veterinary Medicine and Surgery: Small Animal, 1997Human intravenous immunoglobulin (hIVIG) is a preparation of normal polyspecific IgG obtained from the plasma of healthy blood donors. Although purified immunoglobulins were initially developed for treatment of primary immunodeficiency syndromes, they have since been documented to be effective in the treatment of some immune-mediated diseases such as ...
J. Catharine +2 more
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Intravenous Immunoglobulin and Atherosclerosis
Clinical Reviews in Allergy & Immunology, 2005Several inflammatory and immunological factors have been established as important contributors to atherogenesis. Among these, oxidized low-density lipoprotein (oxLDL) play a central role in the initiation and progression of atherosclerotic lesions. In atherosclerotic lesions, oxLDL was also found to co-localize with beta2-glycoprotein I (beta2-GPI ...
Eiji, Matsuura +3 more
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Intravenous Immunoglobulin and Fibrosis
Clinical Reviews in Allergy & Immunology, 2005Fibrosis is a pathological process that includes scar formation and overproduction of extracellular matrix by the connective tissue as a response to tissue damage. Pathologies include pathological scarring as colloid and hypertrophic scars in the skin, cirrhosis of liver and gallbladder, pulmonary and bone-marrow fibrosis, and scleroderma.
Vered, Molina +2 more
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Immunomodulation by Intravenous Immunoglobulin
Journal of Pediatric Hematology/Oncology, 1990In 1980, it was observed in a child with idiopathic thrombocytopenic purpura (ITP) that intravenous administration of pooled human immunoglobulin-G (IVIG) was followed by a rapid increase of the platelet count. Prompted by this finding, a pilot study and two prospective multicenter studies on children with ITP were organized.
P, Imbach +7 more
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INTRAVENOUS IMMUNOGLOBULIN PREPARATIONS
The Lancet, 1983P, Stanley, P, Cole
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Intravenous immunoglobulin consensus statement☆☆☆
Journal of Allergy and Clinical Immunology, 2001Intravenous immunoglobulin (IVIG) preparations are a mainstay for a number of disorders that include primary immuno-deficiency, acute inflammatory conditions, hematological disorders, infections, and neuroimmunological disorders. The range of therapeutic activity is attributed to IVIG's myriad action mechanisms.
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