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Abstract We report a case of a premature, growth‐restricted female infant with feeding intolerance and coagulopathy, treated initially for sepsis, who progressed to neonatal acute liver failure and end‐stage hepatic encephalopathy after a prolonged hospitalization with extensive diagnostic evaluation, and was found by autopsy to have histopathologic ...
Adrienne Bruder +3 more
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Abstract Objectives Biliary atresia (BA) is a cholangiopathy characterized by obstruction of the intrahepatic and extrahepatic bile ducts. Hepatic portoenterostomy (HPE) is the primary palliative treatment and there is still an urgent need to improve post‐HPE management.
Bianca Ferraz de Almeida Silva +7 more
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[Intravenous immunoglobulins: this is it!].
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Use of Intravenous Immunoglobulins in Sepsis Therapy—A Clinical View
Sepsis is a life-threatening organ dysfunction, defined by a dysregulated host immune response to infection. During sepsis, the finely tuned system of immunity, inflammation and anti-inflammation is disturbed in a variety of ways.
Axel Nierhaus +2 more
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Granulomatosis with polyangiitis, formerly known as Wegener's granulomatosis or disease, is a systemic, necrotizing small-vessel vasculitis, belonging to the group of anti-neutrophil cytoplasm antibody vasculitis.
Sara Tenti +2 more
exaly +2 more sources
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Safety of Intravenous Immunoglobulin
Archives of Neurology, 1993The current position of intravenous immunoglobulin (IVIG) in neurology is similar to that of plasmapheresis 10 years ago. Therapeutic claims have been made for an increasing number of neurologic disorders, based on small, uncontrolled studies. With the recent publication of a controlled trial of IVIG treatment in Guillain-Barre syndrome, 1 and trials ...
C A, Thornton, M, Ballow
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Intravenous Immunoglobulin and Fibrosis
Clinical Reviews in Allergy & Immunology, 2005Fibrosis is a pathological process that includes scar formation and overproduction of extracellular matrix by the connective tissue as a response to tissue damage. Pathologies include pathological scarring as colloid and hypertrophic scars in the skin, cirrhosis of liver and gallbladder, pulmonary and bone-marrow fibrosis, and scleroderma.
Vered, Molina +2 more
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Intravenous Immunoglobulin and Atherosclerosis
Clinical Reviews in Allergy & Immunology, 2005Several inflammatory and immunological factors have been established as important contributors to atherogenesis. Among these, oxidized low-density lipoprotein (oxLDL) play a central role in the initiation and progression of atherosclerotic lesions. In atherosclerotic lesions, oxLDL was also found to co-localize with beta2-glycoprotein I (beta2-GPI ...
Eiji, Matsuura +3 more
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Therapeutic intravenous immunoglobulins
Molecular Immunology, 2005Intravenous immunoglobulins (IVIg) are concentrated formulations of human IgG prepared by industrial fractionation of large pools of individual plasma donations. IVIg were developed 20 years ago for the prophylaxis support of immunodeficient patients.
Réal, Lemieux +2 more
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Immunomodulation by Intravenous Immunoglobulin
Journal of Pediatric Hematology/Oncology, 1990In 1980, it was observed in a child with idiopathic thrombocytopenic purpura (ITP) that intravenous administration of pooled human immunoglobulin-G (IVIG) was followed by a rapid increase of the platelet count. Prompted by this finding, a pilot study and two prospective multicenter studies on children with ITP were organized.
P, Imbach +7 more
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