Results 161 to 170 of about 107,995 (302)

Health Risks from Microplastics in Intravenous Infusions: Evidence from Italy, Spain, and Ecuador. [PDF]

Toxics
Casella C, Cornelli U, Zanoni G, Moncayo P, Ramos-Guerrero L.   +4 more
europepmc   +1 more source

Intravenous Infusions of Glycerol Versus Propylene Glycol for the Regulation of Negative Energy Balance in Sheep: A Randomized Trial. [PDF]

Animals (Basel), 2019
Kalyesubula M, Rosov A, Alon T, Moallem U, Dvir H.   +4 more
europepmc   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Intravenous infusions of mesenchymal stromal cells have cumulative beneficial effects in a porcine model of chronic ischaemic cardiomyopathy. [PDF]

Cardiovasc Res
Tang XL, Wysoczynski M, Gumpert AM, Solanki M, Li Y, Wu WJ, Zheng S, Ruble H, Li H, Stowers H, Zheng S, Ou Q, Tanveer N, Slezak J, Kalra DK, Bolli R.   +15 more
europepmc   +1 more source

A Phase 1 Randomized Study of Single Intravenous Infusions of the Novel Nitroxyl Donor BMS-986231 in Healthy Volunteers. [PDF]

J Clin Pharmacol, 2019
Cowart D, Venuti RP, Lynch K, Guptill JT, Noveck RJ, Foo SY.   +5 more
europepmc   +1 more source

Melarsoprol-Free Drug Combinations for Second-Stage Gambian Sleeping Sickness: The Way to Go. [PDF]

, 2007
Balasegaram, Brun, F. Chappuis, Priotto, P  pin, P  pin, Van Nieuwenhove   +6 more
core   +2 more sources

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Higher Rates of Delay in Starting Advanced Inflammatory Bowel Disease Therapies Linked to Insurance Delays, Intravenous Infusions, and Lack of Pharmacy Support. [PDF]

Clin Transl Gastroenterol
Gottesman S, Xiao K, Nguyen HP, Hernandez E, Saweris E, Jagannathan P, Jafri F, Davis J, Tong K, Tang Z, Gaidos JKJ, Feagins LA.   +11 more
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Pharmacokinetics of isavuconazole at different target sites in healthy volunteers after single and multiple intravenous infusions. [PDF]

J Antimicrob Chemother
Bergmann F, Wölfl-Duchek M, Jorda A, Al Jalali V, Leutzendorff A, Sanz-Codina M, Gompelmann D, Trimmel K, Weber M, Eberl S, Van Os W, Minichmayr IK, Reiter B, Stimpfl T, Idzko M, Zeitlinger M.   +15 more
europepmc   +1 more source