A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia. [PDF]
Reed GA+14 more
europepmc +1 more source
Septicaemia from prolonged intravenous infusions. [PDF]
M L Thong, Lay Tay
openalex +1 more source
CLDN18.2 is a highly selective biomarker exposed in gastric cancer. A CLDN18.2‐specific antibody 1D5 conjugated fluorescence‐magnetic nanoparticle is developed for image‐guided precision theragnostics. Under the assistance of sensitive FMI and deep‐penetrating MPI for tracing and timing the optimal nanoparticle dosage, combining α‐PD1 therapy with ...
Xueying Wang+14 more
wiley +1 more source
Blood ethanol concentrations during and following constant‐rate intravenous infusion of alcohol [PDF]
Paul K. Wilkinson+5 more
openalex +1 more source
Postoperative cognitive dysfunction (POCD) remains a challenge with no effective treatments. This study introduces a novel hydrogen‐gene therapy strategy, combining focused ultrasound and siRNA delivery via hydrogen emitters, to repair neuroinflammation in a precise and controlled manner.
Ruonan Zhan+11 more
wiley +1 more source
Pharmacokinetics of cefozopran by single and multiple intravenous infusions in healthy Chinese volunteers. [PDF]
Wu GL+6 more
europepmc +1 more source
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han+10 more
wiley +1 more source
NORMALIZATION OF FASTING HYPERGLUCAGONEMIA AND EXCESSIVE GLUCAGON RESPONSES TO INTRAVENOUS ARGININE IN HUMAN DIABETES MELLITUS BY PROLONGED INFUSION OF INSULIN [PDF]
John E. Gerich+6 more
openalex +1 more source
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan+12 more
wiley +1 more source
Intravenous energy infusion in lambs: effects on nitrogen retentin, plasma free amino acids and plasma urea nitrogen [PDF]
B. Eskeland+2 more
openalex +1 more source