Results 261 to 270 of about 2,127,832 (378)
A PRELIMINARY REPORT ON THE TREATMENT OF ADVANCED PULMONARY TUBERCULOSIS BY INTRAVENOUS INJECTIONS OF IODOFORM [PDF]
T. W. Dewar
openalex +1 more source
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li+9 more
wiley +1 more source
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi+20 more
wiley +1 more source
Endogenous Endophthalmitis Secondary to Prostate Abscess. [PDF]
Saleh NA, Patel S, Quadri S.
europepmc +1 more source
In tumor cells, ENH prompts the interaction between YAP and KPNA2. This interaction enables YAP to translocate into the nucleus, where it enhances the transcription of CCL5. Consequently, this up‐regulation of CCL5 drives the infiltration of tumor‐associated macrophages (TAMs) and their polarization toward the M2 phenotype, ultimately facilitating ...
Yueli Shi+14 more
wiley +1 more source
Combined Transplantation of Mesenchymal Progenitor and Neural Stem Cells to Repair Cervical Spinal Cord Injury. [PDF]
White SV+4 more
europepmc +1 more source
Tumor‐Associated Glycan Exploits Adenosine Receptor 2A Signaling to Facilitate Immune Evasion
This study identifies Globo H ceramide (GHCer) as a novel immune checkpoint molecule that suppresses the activation of conventional T lymphocytes while promoting the differentiation and function of regulatory T cells. The immunosuppressive effects of GHCer are mediated through the activation of the A2AR/cAMP/PKA pathway, which involves its interactions
Jing‐Yan Cheng+13 more
wiley +1 more source
Engineered retargeting to overcome systemic delivery challenges in oncolytic adenoviral therapy. [PDF]
Leparc L, Wakimoto H.
europepmc +1 more source