Recent Advances in mRNA Delivery Systems for Cancer Therapy
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang+9 more
wiley +1 more source
A meta-analysis on application and prospect of cell therapy in the treatment of diabetes mellitus. [PDF]
Li H+10 more
europepmc +1 more source
The One-Hour Ovarian Hyperemia Response to Intravenous Injection of Human Urine in the Immature Rat
Somers H. Sturgis, P Haour
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This work reports a mitochondria‐targeted nanozyme platform, MIL‐Cu1.8S‐TPP/FA, which induces potent cuproptosis via localized delivery of Cu1.8S nanodots to mitochondria. Surface‐anchoring these nanodots onto MIL‐88B metal‐organic frameworks enhances both passive and active tumor targeting.
Chenguang Liu+8 more
wiley +1 more source
Cryoablation and Intratumoral Immunotherapy for Breast Cancer: A Future Path to Cost-Effective De-Escalation for Larger Tumors, Lymph Nodes and Metastatic Disease. [PDF]
Fermanian J+6 more
europepmc +1 more source
The excretion of prolan after intravenous injection into the rabbit
A. S. Parkes, William E. White
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This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan+6 more
wiley +1 more source
The effects of hyperglycemia on brain physiology in a healthy and injured state: An experimental pig study with state-of-the-art multimodal neuromonitoring. [PDF]
Svedung Wettervik T+4 more
europepmc +1 more source
Spatiotemporal Regulation of STING Activity by Linear Ubiquitination Governs Antiviral Immunity
This study uncovers a spatiotemporal regulation of STING activity by linear ubiquitination in antiviral immunity. At the early stage of the infection, LUBAC promotes STING linear ubiquitination to drive its trafficking from the ER to the Golgi apparatus for activation.
Yong Zhang+13 more
wiley +1 more source
Intravenous mesenchymal stem cell transplantation mitigates pulmonary vascular remodeling but poses dose related risks in a pulmonary veno-occlusive disease model. [PDF]
Katagiri J+6 more
europepmc +1 more source