Results 11 to 20 of about 215,713 (138)

Labetalol infusion for refractory hypertension causing severe hypotension and bradycardia: an issue of patient safety [PDF]

open access: yesPatient Safety in Surgery, 2008
Incremental doses of intravenous labetalol are safe and effective and, at times, such therapy may need to be augmented by a continuous infusion of labetalol to control severe hypertension.
Papadimos Thomas J   +2 more
doaj   +2 more sources

Effectiveness and safety of intravenous labetalol in severe pre-eclampsia and eclampsia at a teaching institution in Chhattisgarh

open access: yesJournal of Family Medicine and Primary Care
Introduction: Severe hypertension in pregnancy deserves prompt recognition and urgent effective reduction in order to reduce the risk of complications such as eclampsia and HELLP syndrome and to achieve desirable neonatal outcomes.
Rachna Jain, Sangeeta Raman Jogi
doaj   +2 more sources

Labetalol Pretreatment Reduces Blood Pressure Instability During Surgical Resection of Pheochromocytoma

open access: yesJournal of the Formosan Medical Association, 2006
To evaluate the effect of pretreatment with the mixed alpha- and beta-adrenergic blocker, labetalol, on blood pressure instability during surgical resection of pheochromocytoma. Methods: Blood pressure stability and surgical results were compared between
Peter Chi-Ho Chung   +4 more
doaj   +2 more sources

Development and Evaluation of a Physiologically Based Pharmacokinetic Model of Labetalol in Healthy and Diseased Populations

open access: yesPharmaceutics, 2022
Labetalol is a drug that exhibits both alpha and beta-adrenergic receptor-blocking properties. The American Heart Association/American Stroke Association (AHA/ASA) has recommended labetalol as an initial treatment option for the management of severe ...
Hafsa Hafsa   +9 more
doaj   +2 more sources

Intravenous nicardipine and labetalol use in hypertensive patients with signs or symptoms suggestive of end-organ damage in the emergency department: a subgroup analysis of the CLUE trial

open access: yesBMJ Open, 2013
Objective To compare the efficacy of Food and Drug Administration recommended dosing of nicardipine versus labetalol for the management of hypertensive patients with signs and/or symptoms (S/S) suggestive of end-organ damage (EOD).Design Secondary ...
Brian Hiestand   +14 more
doaj   +2 more sources

Treatment of post-coarctectomy hypertension with labetalol: a 9-year single-center experience [PDF]

open access: yes, 2022
Background: Although considering the pathophysiology of post-coarctectomy hypertension, beta-blockers should be effective, experience with labetalol for treatment is limited in the literature.
Siersma, C.   +4 more
core   +1 more source

Intravenous labetalol vs. oral nifedipine in control of hypertensive emergencies in severe pre-eclampsia and eclampsia: a randomized control trial [PDF]

open access: yes, 2021
Background: Pre-eclampsia is a disorder peculiar to human pregnancy and accounts for a considerable proportion of both maternal and perinatal deaths. This study was undertaken to compare the efficacy of labetalol versus nifedepine in the treatment of ...
M., Veerendrakumar C.   +3 more
core   +1 more source

Comparative study of intravenous hydralazine and labetalol in severe hypertensive disorders of pregnancy [PDF]

open access: yes, 2020
Background: Hypertensive disorders of pregnancy are among the most common medical complications of pregnancy and major cause of maternal, fetal and neonatal morbidity and mortality.
Kumar, Raj   +3 more
core   +1 more source

Effect of perioperative magnesium sulfate and labetalol infusion on peripheral perfusion and postoperative pain in nasal surgery: a randomized controlled trial

open access: yesPatient Safety in Surgery, 2022
Background Maintenance of adequate peripheral perfusion during controlled hypotension is necessary for patient safety and improved surgical outcomes during controlled hypotension in nasal surgery.
Alshaimaa Abdel Fattah Kamel   +3 more
doaj   +1 more source

Comparing Intravenous Labetalol and Intravenous Hydralazine for Managing Severe Gestational Hypertension

open access: yesCureus, 2023
Background Hypertensive disorders of pregnancy are the leading causes of both maternal morbidity and maternal mortality. Hypertensive disorders are acute obstetric emergencies, which refer to various life-threatening medical challenges known to develop during pregnancy, labor, and delivery, requiring urgent attention to reduce blood pressure (BP) for ...
Ehikioya, Eustace   +9 more
openaire   +2 more sources

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