Results 1 to 10 of about 7,444 (161)

Comparative study of labetalol and nifedipine in management of hypertensive disorders of pregnancy in BRIMS tertiary care center [PDF]

New Indian Journal of OBGYN, 2021
Objective: To compare the efficacy and safety of oral labetalol and nifedipine in hypertensive disorder of pregnancy. Methods: A prospective comparative study was carried out in obstetrics and gynaecology department BRIMS tertiary care center between ...
Uma B Deshmukh, Savitha A, Sangeeta Tengli   +2 more
doaj   +1 more source

Formulation and In-Vitro, Ex-Vivo, and In-Vivo Evaluation of Mucoadhesive Buccal Tablets Containing Labetalol Hydrochloride for Enhancement of Systemic Bioavailability [PDF]

Journal of Advanced Pharmacy Research, 2022
Objective: Labetalol hydrochloride is an alpha/beta adrenoceptor blocker that undergoes comprehensive first pass-metabolism resulting in a low oral bioavailability.
Fatma Bakr, Moetaza Soliman, Hassan Elsabbagh   +2 more
doaj   +1 more source

Protective effects of Zingiber officinale extract on myocardium and placenta against labetalol-induced histopathological, immune-histochemical, and ultrastructural alterations in pregnant rats

Journal of Basic and Applied Zoology, 2021
Background Labetalol is an antihypertensive drug commonly used in obstetrics for both long-term treatment and the acute management of severe maternal hypertension.
Hend T. El-Borm, Marwa N. Atallah
doaj   +1 more source

Modulatory effect of ginger on skeletal malformations, cell cycle, apoptosis and structural changes in the liver of rat fetuses prenatally exposed to labetalol

Beni-Suef University Journal of Basic and Applied Sciences, 2023
Background Drug-induced liver damage with clinical symptoms has been related to labetalol in a number of instances. In addition to having a wide range of anti-inflammatory and antioxidant qualities, ginger also includes biotrace that are crucial in the ...
Hend T. El-Borm, Marwa S. Gobara, Gamal M. Badawy   +2 more
doaj   +1 more source

Labetalol and soluble endoglin aggravate bile acid retention in mice with ethinylestradiol-induced cholestasis

Frontiers in Pharmacology, 2023
Labetalol is used for the therapy of hypertension in preeclampsia. Preeclampsia is characterized by high soluble endoglin (sEng) concentration in plasma and coincides with intrahepatic cholestasis during pregnancy (ICP), which threatens the fetus with ...
Ivone Cristina Igreja Sá, Katarina Tripska, Fatemeh Alaei Faradonbeh, Milos Hroch, Hana Lastuvkova, Jolana Schreiberova, Marian Kacerovsky, Miguel Pericacho, Petr Nachtigal, Stanislav Micuda   +9 more
doaj   +1 more source

Effect of perioperative magnesium sulfate and labetalol infusion on peripheral perfusion and postoperative pain in nasal surgery: a randomized controlled trial

Patient Safety in Surgery, 2022
Background Maintenance of adequate peripheral perfusion during controlled hypotension is necessary for patient safety and improved surgical outcomes during controlled hypotension in nasal surgery.
Alshaimaa Abdel Fattah Kamel, Marwa Mohamed Medhat, Dina Abdelhameed Elsadek Salem, Sara Mohamed Abdel Naby   +3 more
doaj   +1 more source

Comparison of Labetalol and Nitroglycerine,s Effects on Deliberate Hypotension in Septo-Rhinoplasty Ssurgery, a Randomized Clinical Trial [PDF]

Reviews in Clinical Medicine, 2020
Introduction:Bleeding during ENT surgeries may contribute to impaired view. The less blood in surgical filed, the better quality and more surgeon’s satisfaction is expected. Deliberate hypotension is a technique to achieve this goal.
Majid Rrazavi, Mona Najaf Najafi, Mahnaz Ahmadi, Iman Kashani   +3 more
doaj   +3 more sources

Comparison of Labetalol and Nitroglycerine on Intraoperative Bleeding in Patients Who Underwent Dacryocystorhinostomy

Acta Medica Iranica, 2020
The bleeding during dacryocystorhinostomy (DCR) surgery is one of the main complications that led to the surgeon’s dissatisfaction and increased the duration of the operation.
Mehdi Sanatkar, Alireza Ebrahim Soltani, Alireza Takzare   +2 more
doaj   +1 more source

Intra-Arterial Labetalol and Nitroglycerin in Preventing Radial Artery Spasm Following Transradial Angiography: A New Approach [PDF]

Pharmaceutical Sciences, 2020
Background: Radial artery spasm (RAS) resulted from decreasing blood flow and activation of vasomotor system leads to a decrease in artery diameter, perfusion and patency, and increase the risk of procedure failure.
Gohar Eslami, Samad Golshani, Mahmood Moosazadeh, Faezeh Shadfar   +3 more
doaj   +1 more source

Comparative study of the effect of two different doses of intravenous labetalol on the cardiovascular response to endotracheal extubation [PDF]

Journal of Cardiovascular and Thoracic Research, 2023
Introduction: Providing a stable hemodynamic in extubation is important. We aimed to compare the effect of two different doses of intravenous labetalol on the cardiovascular response to endotracheal extubation. Methods: This double-blind randomized trial
Hamidreza Shetabi, Behzad Nazemroaya, Hosein Mahjobipoor, Sanaz Majidi   +3 more
doaj   +1 more source