Determination of potential genotoxic impurities in labetalol hydrochloride by HPLC-MS/MS method [PDF]
Journal of Hebei University of Science and TechnologyIn order to better control the potential genotoxic impurities in labetalol hydrochloride and ensure the safety of medication, a high-performance liquid chromatography-mass spectrometry(HPLC-MS/MS) method was established to detect potential genotoxic ...
Jiarui HAN +3 more
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Labetalol infusion for refractory hypertension causing severe hypotension and bradycardia: an issue of patient safety [PDF]
Patient Safety in Surgery, 2008 Incremental doses of intravenous labetalol are safe and effective and, at times, such therapy may need to be augmented by a continuous infusion of labetalol to control severe hypertension.
Papadimos Thomas J +2 more
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Hypertension in Pregnancy, 2017 Objective: To determine whether oral labetalol is associated with a shorter time to blood pressure control compared to oral extended release nifedipine for management of persistent postpartum hypertension.
Kathryn J. Sharma +2 more
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Labetalol, Nifedipine, and Methyldopa for the Management of Hypertensive Disorders in Pregnancy in Iran: A Cost‐Effectiveness Analysis [PDF]
Health Science ReportsBackground and Aims Hypertensive disorders in pregnancy create major clinical and economic burdens on maternal health services, making evidence on efficient resource allocation and cost‐effectiveness essential for treatment decisions.
Zahra Goudarzi +2 more
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Hypertension‐related morbidity after delivery discharge: A comparison of nifedipine versus labetalol [PDF]
PregnancyObjective To evaluate rates of hypertension‐related morbidity after delivery discharge among individuals on nifedipine versus labetalol monotherapy.
Sonya Fabricant +6 more
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The therapeutic effects of labetalol in chronic stress- and immuno-agonist-induced cough hypersensitivity and lung inflammation involve reducing interferon-γ-producing T lymphocytes [PDF]
ERJ Open ResearchBackground Psychological stress correlates with chronic cough, which is often triggered by respiratory viruses. Chronic stress promotes sympathetic nerves to release norepinephrine and neuropeptide Y.
Tongtong Song +7 more
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Lipid Emulsion Mitigates the Cardiotoxic Effects of Labetalol in Rat Cardiomyoblasts
CellsLipid emulsion has recently emerged as an effective agent for improving the cardiotoxicity of highly lipophilic drugs. However, its effect on cardiotoxicity induced by labetalol, a nonselective beta-blocker, remains unknown.
Gyujin Sim +5 more
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Labetalol Pretreatment Reduces Blood Pressure Instability During Surgical Resection of Pheochromocytoma [PDF]
Journal of the Formosan Medical Association, 2006 To evaluate the effect of pretreatment with the mixed alpha- and beta-adrenergic blocker, labetalol, on blood pressure instability during surgical resection of pheochromocytoma. Methods: Blood pressure stability and surgical results were compared between
Peter Chi-Ho Chung +4 more
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Comparative study of labetalol and nifedipine in management of hypertensive disorders of pregnancy in BRIMS tertiary care center [PDF]
New Indian Journal of OBGYN, 2021 Objective: To compare the efficacy and safety of oral labetalol and nifedipine in hypertensive disorder of pregnancy. Methods: A prospective comparative study was carried out in obstetrics and gynaecology department BRIMS tertiary care center between ...
Uma B Deshmukh +2 more
doaj +1 more source
Majalah Obstetri dan GinekologiHIGHLIGHTS • All three medications (nifedipine, methyldopa, and labetalol) are viable first-line options for treating severe preeclampsia in pregnanc • Oral nifedipine may be faster at lowering blood pressure in severe preeclampsia than methyldopa or ...
Bambang Rahardjo +2 more
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