HLA gene expression is altered in whole blood and placenta from women who later developed preeclampsia [PDF]
, 2017 Preeclampsia is a multi-system disease that significantly contributes to maternal and fetal morbidity and mortality. In this study, we used a non-biased microarray approach to identify dysregulated genes in maternal whole blood samples which may be ...
Akehurst, Christine +8 more
core +1 more source
Hypertension in Pregnancy, 2017 Objective: To determine whether oral labetalol is associated with a shorter time to blood pressure control compared to oral extended release nifedipine for management of persistent postpartum hypertension.
Kathryn J. Sharma +2 more
doaj +1 more source
Formosan Journal of Surgery, 2018 Background: Excessive bleeding occurs from mucosal edges during functional endoscopic sinus surgery (FESS). This could decrease the visibility of the surgeon and increase the risk incidence of complications. The current study aimed to evaluate the effect
Aliakbar Eghbal +5 more
doaj +1 more source
Beta-Blocking Agents and Electroconvulsive Therapy [PDF]
, 2007 In this review we want to summarize the results of the placebo-controlled randomized clinical trials with betablocking adrenergic agents during electroconvulsive therapy (ECT), and review the effect on seizure duration and cardiovascular variables.
Birkenhäger, T.K. (Tom) +6 more
core +1 more source
Intravenous Labetalol vs Intravenous Clonidine for Attenuation of Haemodynamic Responses during Laryngoscopy and Intubation in Controlled Hypertensive Patients Undergoing General Anaesthesia- A Randomised Clinical Trial [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Laryngoscopy and endotracheal intubation during general anaesthesia are associated with haemodynamic surges which can be detrimental, particularly if there is pre-existing hypertension or cardiovascular disease. Intravenous (i.v.) labetalol,
Vijay Singh +4 more
doaj +1 more source
Raynaud's phenomenon of the nipple as a side-effect of labetalol: Case report and literature review
Case Reports in Women's Health, 2019 Raynaud's phenomenon of the nipple is an unusual side-effect of labetalol use. There is one official report from the United Kingdom. The present case concerns a 30-year-old woman, gravida 1, para 0, who developed pre-eclampsia and was treated with ...
Jesus Avila-Vega +2 more
doaj +1 more source
Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans : lost in translation [PDF]
, 2013 We greatly appreciate the comments offered by Drs Rolle, Takematsu, and Hoffman and the opportunity to put our work into a wider perspective. We share the view that our work does not reflect the clinical situation but rather provides a proof of mechanism
Boehrer +26 more
core +1 more source
Labetalol-Induced Hepatotoxicity during Pregnancy: A Case Report
American Journal of Perinatology Reports, 2020 Background Drug-induced liver injury is a common cause of transaminitis, occurring in up to 5% of patients who are hospitalized for liver failure. In pregnancy, transaminitis is seen in conditions which may require expedited delivery.
Anna Whelan +4 more
doaj +1 more source
Micro-RNAs of the miR-15 family modulate cardiomyocyte survival and cardiac repair [PDF]
, 2015 A family of microRNAs, called the miR-15 family, which includes miR-195, are shown to be up-regulated during pathological cardiac remodeling and repress the expression of mRNAs required for cell proliferation and survival, with consequent loss of ...
Olson, Eric N., van Rooij, Eva
core +1 more source
Pregnancy-Related Hormones Increase UGT1A1-Mediated Labetalol Metabolism in Human Hepatocytes
Frontiers in Pharmacology, 2021 Pregnancy-related hormones (PRH) are recognized as important regulators of hepatic cytochrome P450 enzyme expression and function. However, the impact of PRH on the hepatic expression and function of uridine diphosphate glucuronosyltransferases (UGTs ...
Raju Khatri +11 more
doaj +1 more source