Formulation and In-Vitro, Ex-Vivo, and In-Vivo Evaluation of Mucoadhesive Buccal Tablets Containing Labetalol Hydrochloride for Enhancement of Systemic Bioavailability [PDF]
Journal of Advanced Pharmacy Research, 2022 Objective: Labetalol hydrochloride is an alpha/beta adrenoceptor blocker that undergoes comprehensive first pass-metabolism resulting in a low oral bioavailability.
Fatma Bakr +2 more
doaj +1 more source
Postpartum blood pressure trends and time in target range during remote blood pressure monitoring [PDF]
Pregnancy (Hoboken)Abstract Introduction Postpartum remote blood pressure monitoring (RBPM) programs have emerged as an important adjunct to the management of hypertensive disorders of pregnancy (HDP). These programs have demonstrated robust patient participation and satisfaction with reduced readmissions and severe maternal morbidity. Despite this, data describing blood
Shim S +6 more
europepmc +2 more sources
Journal of Basic and Applied Zoology, 2021 Background Labetalol is an antihypertensive drug commonly used in obstetrics for both long-term treatment and the acute management of severe maternal hypertension.
Hend T. El-Borm, Marwa N. Atallah
doaj +1 more source
Beni-Suef University Journal of Basic and Applied Sciences, 2023 Background Drug-induced liver damage with clinical symptoms has been related to labetalol in a number of instances. In addition to having a wide range of anti-inflammatory and antioxidant qualities, ginger also includes biotrace that are crucial in the ...
Hend T. El-Borm +2 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Labetalol is used for the therapy of hypertension in preeclampsia. Preeclampsia is characterized by high soluble endoglin (sEng) concentration in plasma and coincides with intrahepatic cholestasis during pregnancy (ICP), which threatens the fetus with ...
Ivone Cristina Igreja Sá +9 more
doaj +1 more source
Patient Safety in Surgery, 2022 Background Maintenance of adequate peripheral perfusion during controlled hypotension is necessary for patient safety and improved surgical outcomes during controlled hypotension in nasal surgery.
Alshaimaa Abdel Fattah Kamel +3 more
doaj +1 more source
Treatment of post-coarctectomy hypertension with labetalol: a 9-year single-center experience [PDF]
, 2022 Background: Although considering the pathophysiology of post-coarctectomy hypertension, beta-blockers should be effective, experience with labetalol for treatment is limited in the literature.
Siersma, C. +4 more
core +1 more source
Comparison of Labetalol and Nitroglycerine,s Effects on Deliberate Hypotension in Septo-Rhinoplasty Ssurgery, a Randomized Clinical Trial [PDF]
Reviews in Clinical Medicine, 2020 Introduction:Bleeding during ENT surgeries may contribute to impaired view. The less blood in surgical filed, the better quality and more surgeon’s satisfaction is expected. Deliberate hypotension is a technique to achieve this goal.
Majid Rrazavi +3 more
doaj +3 more sources
Comparative study of the effect of two different doses of intravenous labetalol on the cardiovascular response to endotracheal extubation [PDF]
Journal of Cardiovascular and Thoracic Research, 2023 Introduction: Providing a stable hemodynamic in extubation is important. We aimed to compare the effect of two different doses of intravenous labetalol on the cardiovascular response to endotracheal extubation. Methods: This double-blind randomized trial
Hamidreza Shetabi +3 more
doaj +1 more source
Intra-Arterial Labetalol and Nitroglycerin in Preventing Radial Artery Spasm Following Transradial Angiography: A New Approach [PDF]
Pharmaceutical Sciences, 2020 Background: Radial artery spasm (RAS) resulted from decreasing blood flow and activation of vasomotor system leads to a decrease in artery diameter, perfusion and patency, and increase the risk of procedure failure.
Gohar Eslami +3 more
doaj +1 more source