Results 211 to 220 of about 266,509 (337)
Influence of scleral thickness on photodynamic therapy outcomes in central serous chorioretinopathy
Abstract Purpose To test the prognostic role of anterior scleral substantia propria (ASSP) thickness in predicting the 3‐month response after half‐dose photodynamic therapy (PDT) in central serous chorioretinopathy (CSCR) and to assess its clinical relevance of ASSP in different CSCR phenotypes.
Paolo Forte+11 more
wiley +1 more source
Abstract Aim H+ facilitates metabolic blood flow regulation while negatively impacting cardiac contractility. Cardiovascular consequences of conjugate bases accumulating alongside H+ remain unclear. Here, we evaluate the cardiovascular effects of nine prominent carboxylates—particularly lactate, 3‐hydroxybutyrate, and butyrate—linked to metabolic and ...
Casper Homilius+5 more
wiley +1 more source
Abstract Background and Purpose Phentolamine is a non‐selective α‐adrenoreceptor antagonist used to reverse local anaesthesia, for example, during dental procedures when a vasoconstrictor is co‐applied. Phentolamine‐mediated vasodilation leads to faster clearance of injected drugs.
Idil Toklucu+8 more
wiley +1 more source
Abstract Background Diabetic foot osteomyelitis (DFO) is associated with a considerably high risk of incident major amputations, disability and mortality. To assess the effects of a local antibiotic delivery system on the incidence of post‐surgical infective complications in patients with DFO.
Matteo Monami+4 more
wiley +1 more source
ABSTRACT Background Patients undergoing Pectus Excavatum repair with the minimally invasive approach frequently report severe postoperative pain. The goal of the study is to determine the superiority of cryoanalgesia compared to standard of care for return to normal quality of life.
M. Bastianello+30 more
wiley +1 more source
Safety of Intrathecal Clonidine as an Adjuvant to Spinal Anesthesia in Infants and Children
ABSTRACT Introduction Preliminary clinical studies have demonstrated that clonidine is an effective adjuvant to spinal anesthesia in neonates and infants. However, the studies conducted previously have had a limited cohort size of 80–100, potentially limiting an accurate measure of its safety.
Grant Heydinger+7 more
wiley +1 more source
What's new? Increasing evidence suggests that the evaluation of tumor‐infiltrating lymphocytes both at baseline and throughout cancer therapy can be valuable for predicting and monitoring treatment responses. Tumor heterogeneity however complicates the assessment of tumor‐infiltrating lymphocytes.
Mengqi Huang+10 more
wiley +1 more source
This study presents an innovative oral microalgae‐based biosystem to inhibit tumor growth, reduce PD‐1 expression, and activate immune responses of hepatocellular carcinoma. When combined with enhanced irreversible electroporation treatment, it demonstrates a synergistic effect that effectively reduces the tumor burden and enhances the tumor immune ...
Cheng Zeng+8 more
wiley +1 more source
The strategy of ultra‐small Pd loaded covalent organic framework combined with NIR irradiation (TP@Pd+NIR) is developed to reprogram lung redox homeostasis for the synergistic enhancement of acute lung injury immunotherapy via ROS scavenging, M2 directional polarization, NF‐κB pathway inhibition as well as tissue repair acceleration.
Doudou Lei+22 more
wiley +1 more source
Rheumatoid arthritis is an incurable inflammatory autoimmune disease. The cleverly biomimetic nanoplatform integrates nanoenzymes and gene therapeutics and is sequentially modified by guanidinium‐based polymers and macrophage membranes, enhancing the gene silencing capability and reactive oxygen species scavenging efficiency through self‐sustaining ...
Huichao Xie+12 more
wiley +1 more source