Results 211 to 220 of about 61,901 (332)
Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications
Experimental Physiology, EarlyView.Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó +1 more
wiley +1 more source
Reoxygenation of asphyxiated newborn piglets: administration of 100% oxygen causes significantly higher apoptosis in cortical neurons, as compared to 21%. [PDF]
, 2014 Di Felice E +11 more
core +1 more source
Experimental Physiology, EarlyView.Abstract Recanalization by endovascular treatment (EVT) is effective in acute ischaemic stroke caused by large‐vessel occlusion. Better understanding of the pathophysiology could possibly identify targets for improving peri‐procedural management and thereby patient outcome.
Adam Vittrup Heiberg +9 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic overview of the study's methodology and key findings. In a preclinical swine model, doxorubicin administration induced cardiotoxicity, characterized by diffuse fibrotic remodelling and altered electrical function, as assessed by magnetic resonance (MR) imaging and electrophysiological mapping.
Javier Villar‐Valero +7 more
wiley +1 more source
DEN Open, Volume 6, Issue 1, April 2026.ABSTRACT Background Endoscopic full‐thickness resection (EFTR) is an effective treatment method for gastric submucosal tumors (SMTs). We aimed to perform a technical analysis of EFTR in gastric SMT and compare it with the outcome parameters. Method Sixty‐one gastric SMTs from 60 patients were resected using EFTR. The indication criteria: size, 11–30 mm,
Hitoshi Mori +20 more
wiley +1 more source
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
MedComm – Oncology, Volume 5, Issue 1, March 2026.Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
Patients Express Satisfaction With Oral Pain Management During Shock Wave Lithotripsy
International Journal of Urological Nursing, Volume 20, Issue 1, March 2026.ABSTRACT Shock Wave Lithotripsy (SWL) is a technique for treating kidney stones. A Danish university hospital implemented a new pain management strategy focused on oral painkillers instead of intravenous opioid analgesics. This study aimed to evaluate patients' satisfaction with the new strategy during SWL and their overall treatment satisfaction ...
Lisbeth Leinum +3 more
wiley +1 more source