Results 221 to 230 of about 266,509 (337)

Prophylactic Fetal Creatine Supplementation Improves Post‐Asphyxial EEG Recovery and Reduces Seizures in Fetal Sheep: Implications for Hypoxic–Ischemic Encephalopathy

open access: yesAnnals of Neurology, Volume 97, Issue 4, Page 673-687, April 2025.
Objective Hypoxic–ischemic encephalopathy (HIE) is a major cause of perinatal brain injury. Creatine is a dietary supplement that can increase intracellular phosphocreatine to improve the provision of intracellular adenosine triphosphate (ATP) to meet the increase in metabolic demand of oxygen deprivation.
Nhi T. Tran   +9 more
wiley   +1 more source

Current and potential methods to assess kidney structure and morphology in term and preterm neonates

open access: yesThe Anatomical Record, Volume 308, Issue 4, Page 1229-1250, April 2025.
Abstract After birth, the kidney structure in neonates adapt to the functional demands of extrauterine life. Nephrogenesis is complete in the third trimester, but glomeruli, tubuli, and vasculature mature with the rapidly increasing renal blood flow and glomerular filtration. In preterm infants, nephrogenesis remains incomplete and maturation is slower
Eveline Staub
wiley   +1 more source

Effects of Midazolam and Dexmedetomidine on Cognitive Dysfunction Following Open‐Heart Surgery: A Comprehensive Review

open access: yesBrain and Behavior, Volume 15, Issue 4, April 2025.
ABSTRACT Purpose Patients undergoing open‐heart surgery often face significant challenges in postoperative cognitive dysfunction (POCD). There has been growing interest in understanding how anesthesia medications, such as dexmedetomidine (DEX) and midazolam, impact cognitive function in these patients.
Masoomeh Tabari   +3 more
wiley   +1 more source

Magnetic Resonance Imaging as a Readout of CLN5 Gene Therapy Efficacy in Sheep

open access: yesBrain and Behavior, Volume 15, Issue 4, April 2025.
Sheep with CLN5 Batten disease that received combination intracerebroventricular and intravitreal gene therapy underwent MRI scanning to assess global and regional brain volumes and determine the value of MRI to detect therapeutic efficacy. Sheep that were treated pre‐symptomatically underwent longitudinal scanning between 5 and 18 months of age, while
Samantha J. Murray   +11 more
wiley   +1 more source

An Italian Survey on the Management of Pediatric Convulsive Status Epilepticus: More Than Just a Pharmacological Choice

open access: yesBrain and Behavior, Volume 15, Issue 4, April 2025.
A survey exploring specialists’ opinions on the current management of pediatric convulsive status epilepticus (CSE) in Italy confirms that first‐line treatment of pediatric CSE relies on intravenous MDZ and that heterogeneity of therapeutic choices starts from the second‐line treatment. Answers’ variability concerning organizational aspects such as the
Caterina Zanus   +12 more
wiley   +1 more source

Unusual Presentation of Recurrent Vaginal Leiomyoma in Pregnancy: A Rare Case Report and Review of Current Literature

open access: yesClinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT Uterine leiomyomas, commonly known as fibroids, are the most prevalent pelvic tumors in females, affecting 20%–30% of women of reproductive age. These fibroids can lead to significant symptoms and morbidity. Vaginal fibroids are rare as primary vaginal tumors; approximately 300 cases have been documented in medical literature to date. Notably,
John Lugata   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy