Results 181 to 190 of about 51,926 (267)

Should self‐administered voluntary assisted dying be supervised? A Queensland case

Medical Journal of Australia, Volume 222, Issue 8, Page 390-393, May 2025.
Eliana Close, Katrine Del Villar, Ben P White   +2 more
wiley   +1 more source

Pharmacoepidemiology of Oxycodone in the USA: An Observational Study of ARCOS, Medicaid, and Medicare Drug Databases

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT The US continues to battle an opioid crisis, substantially influenced by prescription opioids, with nearly 80 000 opioid‐related deaths in 2023. This study aims to characterize oxycodone's distribution in the United States (US) from 2000 to 2023 using three data sources.
Jay P. Solgama, Apoorva Pradhan, Kenneth L. McCall, Brian J. Piper   +3 more
wiley   +1 more source

Upper Limb Wound Profile in Patients Who Inject Heroin and Fentanyl Mixed With Xylazine. [PDF]

Hand (N Y)
Dos Santos AK, Sisroe Dos Santos TA, Doddala B, Zabel D.   +3 more
europepmc   +1 more source

Managing Drug–Drug Interactions Involving the Non‐Prescription Opioid Loperamide Through Physiologically Based Pharmacokinetic Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Loperamide is a widely used nonprescription peripherally acting opioid indicated for diarrhea. Loperamide undergoes extensive first‐pass metabolism, primarily by cytochrome (CYP) 3A and CYP2C8, with minor contributions from CYP2B6 and CYP2D6, and intestinal efflux by P‐glycoprotein (P‐gp).
Zhu Zhou, Garrett R. Ainslie, Mengyao Li, Jean Dinh, Maciej J. Zamek‐Gliszczynski, Ping Zhao, Mary F. Paine   +6 more
wiley   +1 more source

Benzodiazepine Use Among Individuals with Opioid Use Disorder: A Narrative Review. [PDF]

Subst Abuse Rehabil
Liu Y, Hong Q, Xie X, Shen W, Chen W, Liu H, Zhou W.   +6 more
europepmc   +1 more source

Pharmacometric‐Based Evaluation of Salmeterol and Its Metabolite α‐Hydroxysalmeterol in Plasma and Urine: Practical Implications for Doping Control

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Salmeterol is a commonly used β2‐agonist included on the List of Prohibited Substances and Methods published by the World Anti‐Doping Agency (WADA). We developed a population pharmacokinetic (popPK) model to describe the PK of salmeterol including its major metabolite, α‐hydroxysalmeterol, in plasma and urine after inhalation.
Paul Thoueille, Anne Danion, Morten Hostrup, Michael Petrou, Koen Deventer, Thierry Buclin, François R. Girardin, Irene Mazzoni, Olivier Rabin, Monia Guidi   +9 more
wiley   +1 more source

The Role of Preoperative Antibiotics in Osteosynthesis of the Hand and Wrist: A Retrospective Analysis. [PDF]

J Clin Med
Hunziker A, Kaech I, Gahl B, Mende K, Schaefer DJ, Kaempfen A.   +5 more
europepmc   +1 more source

Cluster‐Randomized Trials in Emergency Care Research

Academic Emergency Medicine, Volume 33, Issue 2, February 2026.
ABSTRACT Objective Cluster‐randomized trials (also called group‐randomized trials) are increasingly common in emergency care research. In such trials, groups of participants are allocated to different interventions based on naturally occurring “clusters,” such as clinics, hospitals, or emergency medical services agencies. In this methodological review,
Howard S. Kim, Jacob M. Schauer, Jody D. Ciolino   +2 more
wiley   +1 more source

Chasing the Dragon Syndrome: A Case of Toxic Leukoencephalopathy and Response to Intravenous Immunoglobulin. [PDF]

Cureus
Puri P, Shadan J, Akhavan M, Farrukh M, Durrani R.   +4 more
europepmc   +1 more source

Procedural separation of appetitive and consummatory behaviors in operant ethanol self‐administration: A review and open‐source analytical framework

Alcohol, Clinical and Experimental Research, Volume 50, Issue 2, February 2026.
This review highlights the biphasic sipper model pioneered by Dr. Hank Samson's laboratory, which separates appetitive and consummatory behaviors in rodent ethanol self‐administration. Over two decades of research using this paradigm reveals that alcohol‐directed behaviors are dynamic, shaped by internal states, cues, and experience.
Olivia A. Colarusso, Jeffrey L. Weiner
wiley   +1 more source