Results 191 to 200 of about 25,875 (276)

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
wiley   +1 more source

Fatal Outcome Following Polysubstance Use: A Case Report of Rhabdomyolysis, Acute Kidney Injury, and Deep Vein Thrombosis. [PDF]

Toxics
Stoeva-Grigorova S, Yarabanova I, Panayotova I, Radeva-Ilieva M, Bonchev G, Tsekov M, Ivanov D, Milkov M, Marinov S, Marinov P, Zlateva S.   +10 more
europepmc   +1 more source

A Multispecies Systematic and Critical Review of Intranasal Administration in Veterinary Anaesthesia and Emergency Care: Promising Evidence and Overlooked Challenges

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This review evaluates the clinical potential and limitations of intranasal (IN) drug administration in veterinary anaesthesia and emergency care. IN delivery can provide clinically relevant sedation, analgesia and drug reversal, but its success is not universally reliable and is strongly influenced by species‐specific anatomy, formulation ...
Majid Jafarbeglou
wiley   +1 more source

Safety of Intravenous Methamphetamine in Patients Taking Mirtazapine: A Two-Site Phase 1b Randomized Controlled Trial. [PDF]

J Clin Psychopharmacol
Black F, Santos GM, McMahan VM, Fraser A, Clark J, Sturgeon L, Walker J, Kochanska M, Shoptaw S, Coffin PO.   +9 more
europepmc   +1 more source

A Primate‐Specific lncRNA LINC01021 Contributes to Cellular and Organismal Aging via DAZAP1‐Dependent Destabilization of RBMX

Aging Cell, Volume 25, Issue 7, July 2026.
Primate‐specific lncRNA LINC01021 promotes aging by enhancing cellular senescence and accelerating aspects of organismal decline. Mechanistically, LINC01021 induces DAZAP1‐mediated destabilization of RBMX, activating the P53 pathway and establishing a primate‐specific regulatory axis in aging.
Yan Zhang, Li Hu, Xin Dong, Qinghua Zeng, Meiting Zi, Ayesha Nisar, Sawar Khan, Raoxian Bai, Chonghui Liu, Mingxia Ge, Shaoyan Pu, Gonghua Li, Yonghan He   +12 more
wiley   +1 more source

Monitoring of new psychoactive substances in France: update of addictovigilance data. [PDF]

Eur J Public Health
Autellet A, Lacroix C, Batisse A, Micallef J, Fouilhe N, Le Boisselier R, Peyrière H, Eiden C, French Addictovigilance Network .   +8 more
europepmc   +1 more source

Improving access to direct acting antivirals via a multimodal integrated care program in an addiction medicine clinic

The American Journal on Addictions, Volume 35, Issue 4, Page 534-542, July 2026.
Abstract Background and Objectives Injection drug use is a driver of hepatitis C virus (HCV) transmission, thus integrating HCV care into addiction care is likely necessary for HCV elimination. Here we describe how we integrated HCV care into our addiction medicine (AM) clinic and evaluate its effect on HCV treatment.
Arya Zandvakili, Joseph Rattenni, James Burton, Lakshmi Guduguntla, Marcus Osman, Sayeh Sabbagh, Stephan Arndt, Ben Miskle, Quanhathai Kaewpoowat, Michael Ohl, Andrea Weber, Alison Lynch   +11 more
wiley   +1 more source

Exploring Non-Pharmacological Interventions as Part of Multimodal Management to Prevent Opioid Misuse in Adults Prescribed Opioids for Chronic Pain. [PDF]

J Clin Med
Alrashid MA, Zumot MS, Fredericks S.
europepmc   +1 more source

Brief Report: Opioid‐related disorders increase patient‐directed discharge in admissions for hemorrhagic or ischemic stroke

The American Journal on Addictions, Volume 35, Issue 4, Page 547-550, July 2026.
Abstract Background and Objectives Opioid use has been linked to increased stroke incidence and severity; however, data on effects during acute stroke hospitalization are limited. Methods We used the 2016–2020 National Inpatient Sample to evaluate the effects of opioid disorders on patient‐directed discharge (PDD) and length of stay (LOS) in 3,101,545 ...
Rohan M. Shah, Shiv Patel, Brent Schnipke, Brandon Hamm   +3 more
wiley   +1 more source

An Unusual Presentation of Cutaneous Leishmaniasis in a Patient with Substance Use: A Diagnostic and Management Case Report. [PDF]

Clin Case Rep
Pazoki H, Soleymani E, Kordi S, Fakhar M.   +3 more
europepmc   +1 more source