Results 201 to 210 of about 50,715 (282)

Fatalities in opioid agonist treatment with long-acting injectable buprenorphine. [PDF]

Int J Legal Med
Häkkinen M, Mariottini C, Kriikku P, Ojanperä I.   +3 more
europepmc   +1 more source

Effect of STW 5‐II (Iberogast‐N) on Tolerance to Gastric Gas in Patients With Functional Dyspepsia. The IBO‐2 Study

Neurogastroenterology &Motility, Volume 37, Issue 11, November 2025.
In a parallel, placebo‐controlled study with direct gas infusion into the stomach, STW 5‐II reduced the perception of abdominal symptoms in patients with dyspepsia complaining of bloating when compared to placebo, with a minor effect on gas transit and evacuation, and no effect on visible abdominal distension.
Ariadna Aguilar, Luis Alcala‐Gonzalez, Claudia Barber, Javier Santos, Beatriz Lobo, Carolina Malagelada, Jordi Serra   +6 more
wiley   +1 more source

Clinical Management of Synthetic-Cannabinoid-Induced Psychosis: A Systematic Review of Treatment Strategies and Outcomes. [PDF]

Brain Sci
Mosca A, Chiappini S, Miuli A, Cavallotto C, Pettorruso M, Martinotti G, Schifano F.   +6 more
europepmc   +1 more source

Portal Venous Drainage Modulates Inflammatory and Apoptotic Responses in a Swine Model of Living Donor Intestinal Transplantation

Pediatric Transplantation, Volume 29, Issue 7, November 2025.
Portal venous drainage in a swine model of living‐donor intestinal transplantation promoted a more balanced immunometabolic profile, with early apoptotic modulation and increased IL‐1α expression, suggesting improved mucosal adaptation compared with systemic drainage.
Guilherme F. Paganoti, Uenis Tannuri, Alessandro R. Belon, Josiane O. Gonçalves, Suellen Serafini, Raimundo R. N. Guimarães, Felipe Y. Matsushita, Ana Cristina A. Tannuri   +7 more
wiley   +1 more source

Statewide Prehospital Buprenorphine in Delaware: Two-Years of Paramedic-Initiated Medication for Opioid Use Disorder After Overdose. [PDF]

Dela J Public Health
Wanner GK, Dworkin M, Rosenbaum RA.
europepmc   +1 more source

Aging and the Spectral Properties of Brain Hemodynamics

Advanced Science, Volume 12, Issue 37, October 6, 2025.
As the brain ages, its metabolic demands decline—but not uniformly. Here, spectral slope flattening of resting‐state fMRI signals is proposed as a potential biomarker of pathologic brain aging. A subset of older adults diverges from youthful spectral and metabolic patterns, with changes linked to frontal white matter pathology and regional loss of ...
Ki Yun Park, Abraham Z. Snyder, Manu S. Goyal, Timothy O. Laumann, John J. Lee, Babatunde Adeyemo, Nicholas Metcalf, Andrei G. Vlassenko, Joshua S. Shimony, Eric C. Leuthardt   +9 more
wiley   +1 more source

Childhood neglects: intimate partner violence in PTSD-SUD comorbid patients treated with narrative exposure therapy. [PDF]

Eur J Psychotraumatol
Nolasco Ferreira V, Vigfusdottir J, Breivik E, Jonsbu E, Bell-Mizori AR, Domogalla SA, Tokovska M.   +6 more
europepmc   +1 more source

Long Non‐Coding RNA IGFRIL Couples with PTBP1 to Destabilize IGFBP3 mRNA to Promote the IGF1R‐AKT‐mTOR Axis and Hepatocellular Carcinoma

Advanced Science, Volume 12, Issue 39, October 20, 2025.
The limited understanding of IGFR pathway activation hinders its clinical application in HCC. Here, IGFRIL is identified as a novel non‐coding activator of the IGF1R, which recruits PTBP1 to destabilize IGFBP3 mRNA and activates IGF1R, and proposes IGFRIL as a novel actionable target for HCC patients.
Jing Zhang, Chengming Gao, Haibei Li, Yuying Chen, Liting Yang, Qian Jin, Lan Feng, Xia Wang, Xinyi Liu, Hongxia Chen, Rong Ye, Yuanchao Xue, Huiyun Wang, Musheng Zeng, Ming Yang, Huaiqiang Ju, Chengzhi Gao, Guangming Zhou, Qi Zhang, Qian Zhang, Geng Qin, Yuanfeng Li, Yahui Wang, Aiqing Yang, Anfeng Si, Qingfeng Song, Fuchu He, Pengbo Cao, Gangqiao Zhou   +28 more
wiley   +1 more source

Discriminating evidence - use and misuse of the drug-discrimination test in abuse potential assessment of novel CNS drugs. [PDF]

J Psychopharmacol
Heal DJ, Smith SL, Gosden J, Rowlett J.
europepmc   +1 more source

Illuminating the Unseen and Targeting the Untreatable: Aggregation‐Induced Emission Nanoparticles as Intelligent, Immune‐Compatible Tools for Precision Cancer Theranostics

Aggregate, Volume 6, Issue 10, October 2025.
Rationally engineered AIE nanoparticles can unite deep‐tissue imaging, photodynamic therapy, photothermal therapy, and immune microenvironment reprogramming. Through precise photophysical tuning and targeted delivery, these intelligent nanoplatforms enable real‐time monitoring, potent tumor eradication, and immune activation, offering a versatile and ...
Quazi T. H. Shubhra, Robert Musiol, Huachun Pan, Qiang Cai, Xiaosong He, Xiaojun Cai   +5 more
wiley   +1 more source