Results 81 to 90 of about 50,715 (282)

A Systematic Review of Substance Misuse Treatment Processes and Outcomes as Implemented in Prisons for Men in the UK

Criminal Behaviour and Mental Health, EarlyView.
ABSTRACT Background With a rising prison population, a substantial portion of whom are identified as substance misusers, it is important to understand the availability of treatment pathways, their successes and areas for improvement. Given the likely importance of national factors in criminal justice and substance use service provision, we chose to ...
Kim Barnett, Noor Butt, Rosie Allen, Pauline Goodlad, Anne Krayer, Adam O'Neill, Peter Huxley, Catherine Robinson, Emily Peckham, Rob Poole   +9 more
wiley   +1 more source

The association between drug injection duration and hepatitis C prevalence among people who inject drugs in Iran

Scientific Reports
People who inject drugs (PWID) are at higher risk of hepatitis C virus (HCV) due to their behaviors such as shared injection. Employing appropriate modeling approaches is crucial for accurately evaluating the impact of other variables on outcomes, in ...
Saiedeh Haji-Maghsoudi, Fatemeh Tavakoli, Soheil Mehmandoost, Naser Nasiri, Ali Akbar Haghdoost, Hamid Sharifi   +5 more
doaj   +1 more source

Transcatheter Management of Severe Paravalvular Leak in the Inferior Vena Cava Prosthesis of the TricValve Bicaval Valve System

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT We present a 74‐year‐old female with a history of mechanical aortic and mitral valve implantation and non‐Hodgkin lymphoma. She presented with right sided heart failure due to severe functional tricuspid regurgitation and was treated with transcatheter TricValve bicaval system implantation.
Marcel A. Beijk, Robbert J. De Winter, Berto J. Bouma   +2 more
wiley   +1 more source

Neurotoxicity induced by mephedrone: an up-to-date review [PDF]

, 2017
BACKGROUND: Mephedrone is a β-ketoamphetamine belonging to the family of synthetic cathinones, an emerging class of designer drugs known for their hallucinogenic and psychostimulant properties as well as for their abuse potential.
Busardo', FRANCESCO PAOLO, DI LUCA, Alessandro, Mannocchi, Giulio, Marinelli, Enrico, Pacifici, Roberta, Pantano, Flaminia, Tittarelli, Roberta   +6 more
core   +1 more source

Safety, Tolerability, and Pharmacokinetics of Galcanezumab, an Anti‐CGRP Antibody, in Healthy Chinese Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Galcanezumab is used in several regions, including the United States, Europe, and China, as a preventive treatment for migraine. This study aimed to evaluate the safety, tolerability, and pharmacokinetics (PK) of galcanezumab in healthy Chinese participants.
Jingjing Wang, Nanyang Li, Jinjie He, Jing Zhang, Lili Wang, William Kielbasa, Chenxi Qian, Yanjie Zhang, Liang Wang   +8 more
wiley   +1 more source

Chronic Human Pegivirus 2 without Hepatitis C Virus Co-infection

Emerging Infectious Diseases, 2020
Most human pegivirus 2 (HPgV-2) infections are associated with past or current hepatitis C virus (HCV) infection. HPgV-2 is thought to be a bloodborne virus: higher prevalence of active infection has been found in populations with a history of parenteral
Kelly E. Coller, Veronica Bruce, Michael Cassidy, Jeffrey Gersch, Matthew B. Frankel, Ana Vallari, Gavin Cloherty, John Hackett, Jennifer L. Evans, Kimberly Page, George J. Dawson   +10 more
doaj   +1 more source

Neuroendocrinology meets addiction: Emerging pharmacotherapies on the horizon. [PDF]

J Intern Med
Abstract Alcohol and other substance use disorders (ASUDs) are prevalent and major contributors to global morbidity and mortality. Their impact extends beyond the individual, imposing significant burdens on families, communities, healthcare systems, and society at large.
Loften A, Farokhnia M, Vendruscolo LF, Leggio L.   +3 more
europepmc   +2 more sources

Current practices in managing acutely disturbed patients at three hospitals in Rio de Janeiro-Brazil: a prevalence study [PDF]

, 2002
The medical management of aggressive and violent behaviour is a critical situation for which there is little evidence. In order to prepare for a randomised trial, due to start in the psychiatric emergency rooms of Rio de Janeiro in 2001, a survey of ...
Adams, C.E., Carvalho, A, Coutinho, E, Fagundes, H.M., Gewandszajder, M, Huf, G, Keusen, A, Lopez, J, Oliveira, E.S.   +8 more
core  

Clinical Pharmacogenetics Implementation Consortium Guideline for NAT2 Genotype and Hydralazine Therapy

Clinical Pharmacology &Therapeutics, EarlyView.
Hydralazine is a vasodilator typically used in the treatment of resistant hypertension and heart failure. N‐acetyltransferase 2 (NAT2) catalyzes the metabolism of hydralazine into inactive metabolites. NAT2 poor metabolizers (historically referred to as “slow acetylators”) are predicted to have increased plasma hydralazine concentrations compared with ...
Michael T. Eadon, David W. Hein, Michael A. Andersen, Arlene B. Chapman, Rhonda M. Cooper‐DeHoff, Zeruesenay Desta, Julio D. Duarte, Amanda L. Elchynski, Andrea Gaedigk, Seth E. Karol, Nita A. Limdi, Christelle Lteif, Laura Sosinski, Pablo Zubiaur, Michelle Whirl‐Carrillo, Teri E. Klein, Kelly E. Caudle, Roseann S. Donnelly, José A.G. Agúndez   +18 more
wiley   +1 more source

The prevalence of homelessness and its associated factors among people who inject drugs in Iran: results from nationwide bio-behavioral surveillance surveys in 2020 and 2023

BMC Public Health
Background Homelessness among people who inject drugs (PWID) represents a significant and complex public health challenge. However, few studies have investigated the factors contributing to its prevalence, particularly in the Middle East and North Africa
Seyed Aria Nejadghaderi, Azin Kadkhodamanesh, Soheil Mehmandoost, Meraj Sharifi, Fatemeh Tavakoli, Maliheh Sadat Bazrafshani, Mehrdad Khezri, Hossein Mirzaie, Naser Nasiri, Sakineh Bajelan, Marieh Sattari, Abedin Iranpour, Hamid Sharifi   +12 more
doaj   +1 more source