Results 101 to 110 of about 25,875 (276)

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Diferentes respostas reforçadoras e locomotoras induzidas pela ativação de endocanabinóide em ratos adolescentes e adultos das linhagens Wistar e Shr [PDF]

, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.Várias evidências apontam para a adolescência como um período crítico para o início de uma ampla escala de ...
Pandolfo, Pablo
core  

Current status of substance abuse and HIV infection in Japan

, 2013
Japan has experienced an epidemic of methamphetamine (MAP) abuse three times: the first epidemic was from 1951 to 1957, the second epidemic was from 1970 to 1994, and the third epidemic started in 1995 and continues today.
Shimane, Takuya, Wada, Kiyoshi, Matsumoto, Toshihiko, Funada, Masahiko   +3 more
core   +1 more source

The Effect of Benzodiazepines on Catatonia: A Systematic Review and Meta‐Analysis

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Catatonia is a complex psychomotor syndrome associated with various psychiatric and somatic underlying disorders. Current treatment protocols include benzodiazepines and electroconvulsive therapy (ECT). Despite their widespread use, systematic evidence regarding efficacy and optimal benzodiazepine dosage remains limited.
L. Bot, B. Schotsman, E. Oostra, A. W. Hoogendoorn, B. W. C. Storosum, C. H. M. Planting, H. M. Heller, J. J. B. van der Vlugt, J. G. van Mill, L. J. C. A. Smarius, M. S. Oudijn, M. S. van Noorden, S. M. M. Lange, Y. D. van der Werf, E. van Exel   +14 more
wiley   +1 more source

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source

Patient autonomy and doctor’s concern – a case of intravenous drug abuser

, 2017
Intravenous substance abuse is often associated with physical and psychological harm, and often requires urgent medical attention. We report a case of a young male who presented with life-threatening complications of intravenous drug abuse, but refused ...
Tanuj Kanchan, Alok Atreya, Rajeev K Shah   +2 more
core   +1 more source

The psychoactive effects of repeated ketamine infusions and their mechanistic role in the treatment of alcohol use disorder: Secondary analysis of a randomised controlled trial

Addiction, EarlyView.
Abstract Background and aims Ketamine assisted psychotherapy is a promising new treatment for alcohol use disorder (AUD). The psychoactive effects of repeated intravenous (IV) ketamine infusions in people with AUD and their mechanistic role in treating AUD are largely unknown.
Cassie Bloy, Ananya Sarma, Bethan Marsh, Lorna Hardy, Meryem Grabski, Merve Mollaahmetoglu, Joshua Shotton, Shamhethan Bhaskaran, Anne Lingford‐Hughes, H. Val Curran, Celia Morgan, Will Lawn   +11 more
wiley   +1 more source

Psychopathology, treatment utilization and gender in relation to substance abuse

, 2002
A case-finding investigation was carried out among personnel within various treatment authorities in Stockholm county, with the purpose of identifying and estimating the prevalence of psychopathology among substance abusers known to the treatment ...
Ulla Bertling (19492213)
core  

Stroke And Substance Abuse

, 2017
Introduction: stroke in recreational substance users can be an indirect complication, like endocarditis and cardio embolism in parenteral drug users. With some drug like cocaine, stroke appear to be the result of a direct effect.
A Chitsaz
core   +1 more source

Barriers and facilitators to detoxification from opioid substitution treatment: A mixed‐methods systematic review

Addiction, EarlyView.
Abstract Background and aims Despite the well‐documented benefits of opioid substitution treatment (OST) in treating opioid dependence (OD), many people diagnosed with OD desire to live a drug‐free life. The transition to abstinence involves detoxification: a gradual dose reduction of OST to zero milligrams.
Amy Bagshaw, Suleyman Shah, India Olchefske, Louise M. Paterson, Mike J. Crawford, Anne Lingford‐Hughes   +5 more
wiley   +1 more source