Results 121 to 130 of about 25,875 (276)

Access to highly active antiretroviral therapy for injection drug users: adherence, resistance, and death

Cadernos de Saúde Pública
Injection drug users (IDUs) continue to comprise a major risk group for HIV infection throughout the world and represent the focal population for HIV epidemics in Asia and Eastern Europe/Russia.
David Vlahov, David D. Celentano
doaj  

Executive function and adult homelessness, true impairment or frontal lobology?

Frontiers in Human Neuroscience
Homelessness is associated with multiple risk factors for neurocognitive impairment. Past research with people experiencing homelessness has described “frontal lobe” dysfunction including behavioral disorders and executive cognitive impairments.
Graham Pluck, Graham Pluck
doaj   +1 more source

UK registry analysis of donor substance misuse and outcomes following pancreas transplantation [PDF]

, 2019
\ua9 2019 The Authors. Clinical Transplantation Published by John Wiley & Sons Ltd Substance abuse is unfortunately common in organ donors. Often, these organs are declined for transplant, not only because of concerns around blood-borne virus ...
Tingle SJ, Wilson CH, Ibrahim IK, White SA, Manas DM, Thompson ER, Trotter P, Irwin EA   +7 more
core  

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Syringe exchange programs in Brazil: preliminary assessment of 45 programs

Cadernos de Saúde Pública
The present study aims to evaluate the current operation of Brazilian syringe exchange programs (SEP). After consulting national and regional networks of people working in projects/ programs aiming to reduce drug-related harm, we identified 134 potential
Elize Massard da Fonseca, José Mendes Ribeiro, Neilane Bertoni, Francisco I. Bastos   +3 more
doaj  

Role of cultural ınteraction in tianeptine abuse and different application methods

, 2013
Tianeptin, güçlü antidepresan ve anksiyolitik özelliklere sahip selektif erotonin geri alım artırıcıdır. Benzer ilaçlara göre sedatif, antikolinerjik ve kardiyovasküler yan etkilerinin azlığı nedeniyle kolay tolere edilebilir.
Şen, Ahmet, Erdivanlı, Başar, Ersöz, Tahir, Tomak, Yakup, İlhan, Gökhan, Ergene, Murat Şaban   +5 more
core   +1 more source

Diltiazem N‐oxide, a novel ischaemia‐activated prodrug, prevents ischaemia‐induced ventricular fibrillation without off‐target adverse effects

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ventricular fibrillation (VF) in coronary heart disease accounts for up to 70% of sudden cardiac death. We examined whether diltiazem N‐oxide (DNO) has ischaemia‐selective antiarrhythmic activity. Experimental Approach Randomised and blinded experiments were performed in rat isolated hearts and in anaesthetised rats to ...
Louise M. Hesketh, Gabriel A. Watson, Francesca Mazzacuva, Zoe Hoare, Thomas R. Eykyn, Michael J. Curtis   +5 more
wiley   +1 more source

Characteristics of male and female injecting drug users of the AjUDE-Brasil II Project

Cadernos de Saúde Pública
The object of this study is to compare female and male injection drug users (IDUs) in terms of sociodemographic profile and aspects of their initiation to the use of injection drugs.
Ana Maria de Oliveira Cintra, Waleska Teixeira Caiaffa, Sueli Aparecida Mingoti   +2 more
doaj  

Delivery of nano‐formulated drugs to solid tumours is selectively increased by co‐application of the vascular disrupting agent CA4P

British Journal of Pharmacology, EarlyView.
Background and purpose Nano‐formulated chemotherapeutics prolong systemic availability of drugs and can reduce systemic toxicity, but their accumulation in solid tumours is often limited and unpredictable. Broadly applicable strategies to selectively enhance tumour delivery are lacking.
Annabel Kitowski, Constanze Heise, Stefanie Sperling, Jasmin Hotz, Danica Bajic, Marina Rubey, Kathrin Klar, Georg Höfner, Julien Vollaire, Veronique Josserand, Jean‐Luc Coll, Oliver Thorn‐Seshold, Petar Marinković, Julia Thorn‐Seshold   +13 more
wiley   +1 more source

HIV pre-exposure prophylaxis programmatic preferences among people who inject drugs: findings from a discrete choice experiment

Addiction Science & Clinical Practice
Background Pre-exposure prophylaxis (PrEP) holds promise for decreasing new HIV infections among people who inject drugs (PWID), yet daily oral PrEP use is low, and PrEP modality and delivery strategy preferences in this population remain understudied ...
William H. Eger, Angela R. Bazzi, Chad J. Valasek, Carlos F. Vera, Alicia Harvey-Vera, Steffanie A. Strathdee, Heather A. Pines   +6 more
doaj   +1 more source