Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: individual-patient-data meta-analysis of randomized trials [PDF]
Background: The recommended maximum age and time window for intravenous alteplase treatment of acute ischemic stroke differs between the Europe Union and United States.
Colin Baigent +28 more
core +5 more sources
Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) [PDF]
<p><b>Background and Purpose:</b> The Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) unadjusted results demonstrated that intravenous alteplase is well tolerated and that the effects were comparable with ...
Ahmed, Niaz +19 more
core +2 more sources
Gait and Balance Disorder in Patients with Transient Ischemic Attack or Minor Stroke [Corrigendum]
Li N, Li J, Gao T, Wang D, Du Y, Zhao X. Neuropsychiatr Dis Treat. 2021;17:305–314. The authors have advised that the r value of intravenous thrombolysis in correlation with the Tandem scale in Table 4 and Table S2 is incorrect.
Li N, Li J, Gao T, Wang D, Du Y, Zhao X
doaj
Objective: The gold standard treatment for patients with cerebral infarction (CI) is intravenous thrombolysis, and it is superior to standard therapy in improving functional status.
S.M. SEHWEIL
doaj +1 more source
BackgroundHemorrhagic transformation (HT) is the most serious complication of ischemic stroke patients after intravenous thrombolysis and leads to a poor clinical prognosis.
Miaomiao Yang +4 more
doaj +1 more source
Early recurrent ischemic stroke complicating intravenous thrombolysis for stroke: incidence and association with atrial fibrillation [PDF]
<p><b>Background and Purpose:</b> Mechanisms of early neurologic deterioration after treatment with intravenous, recombinant, tissue-type plasminogen activator (IV rt-PA) include symptomatic intracerebral hemorrhage (SICH) and early ...
Awadh, M. +5 more
core +1 more source
Intravenous Thrombolysis for a Stroke Mimic Patient [PDF]
The authors present the case of a young woman on phentermine and herbal supplements who presented as an acute stroke alert with right-sided facial droop and numbness. She was treated acutely with intravenous tissue plasminogen activator (tPA). However, the workup did not reveal any evidence of cerebrovascular disease or cerebral infarct.
Lilly Nguyen +4 more
openaire +3 more sources
Background and Purpose: Cardiac myxoma is a rare etiology of stroke. Both cerebral microbleeds and cardiac myxoma may increase the risk of intracerebral hemorrhage after intravenous thrombolysis. However, data is still limited.
Aurauma eChutinet +6 more
doaj +1 more source
Revascularization in acute intracranial large vessels occlusion: direct or bridging thrombectomy?
Guidelines for the early management of acute ischemic stroke recommend intravenous thrombolysis followed by endovascular treatment as the first choice for the treatment of stroke with large vessel occlusion within 4.5 h of symptom onset.
YANG Qingwu, ZI Wenjie
doaj +1 more source
Influence of age on outcome from thrombolysis in acute stroke: a controlled comparison in patients from the Virtual International Stroke Trials Archive (VISTA) [PDF]
<p><b>Background and Purpose:</b> Thrombolysis for acute ischemic stroke in patients aged >80 years is not approved in some countries due to limited trial data in the very elderly.
Bluhmki, E. +4 more
core +1 more source

