Results 71 to 80 of about 235,541 (221)

Corneal transplantation: Restoring sight to the blind

open access: yesActa Ophthalmologica, EarlyView.
Abstract Corneal blindness is one of the leading causes of vision loss worldwide. Transplantation of the cornea can restore vision and make blind patients see again. Corneal transplant surgery has undergone major evolution in recent decades with the advent of minimally invasive lamellar surgical approaches such as DMEK and DALK.
Claus Cursiefen
wiley   +1 more source

Intravitreal dexamethasone implants for diabetic macular edema

open access: yesInternational Journal of Ophthalmology, 2018
To evaluate the safety and efficacy of a dexamethasone (DEX) intravitreal implant for diabetic macular edema (DME).Totally 113 eyes of 84 patients were divided in three subgroups: naive patients (n=11), pseudophakic patients (n=72) and phakic patients (n=30).
Alicia Pareja-Ríos   +5 more
openaire   +3 more sources

Clinical outcomes of the PAUL® glaucoma implant for secondary glaucoma

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Secondary glaucoma encompasses a broad spectrum of disease entities arising from diverse ocular pathologies and is often refractory to conventional treatment. Glaucoma drainage devices (GDDs) have therefore become an important surgical option.
Carolin Deubel   +7 more
wiley   +1 more source

Healthcare resource use and costs of diabetic macular oedema for patients with antivascular endothelial growth factor versus a dexamethasone intravitreal implant in Korea: a population-based study

open access: yesBMJ Open, 2019
Objectives To estimate the costs and healthcare resources of patients with diabetic macular oedema (DME) who received intravitreal antivascular endothelial growth factor (anti-VEGF) agents or a dexamethasone intravitreal implant (DEX-implant) in Korea ...
SeungJin Bae   +6 more
doaj   +1 more source

Neovascular glaucoma at a tertiary Centre in Finland, 2008–2024: A retrospective cohort study

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Neovascular glaucoma (NVG) is a refractory secondary glaucoma, yet longitudinal outcome data remain limited. This study reports its aetiologies, treatments and outcomes. Methods Patients with NVG were identified through electronic medical record review.
Gilbert Simons   +3 more
wiley   +1 more source

Dexamethasone intravitreal implant for the treatment of noninfectious uveitis

open access: yesClinical Ophthalmology, 2011
Uveitis can be a sight-threatening eye disease with significant morbidity. Corticosteroids remain the mainstay of treatment of uveitis and provide an effective treatment against ocular inflammation. However, the various modes available for corticosteroid drug delivery can carry significant ocular and systemic side effects which can limit their use in ...
Hunter,Rebecca S, Lobo,Ann-Marie
openaire   +4 more sources

Evaluation of the Safety and Therapeutic Range of Nanosecond Laser Treatment in Rabbits

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Subthreshold, nanosecond laser therapy has potential as a treatment for age‐related macular degeneration; however, the therapeutic range and safety profile have not been fully documented. In this study, rabbits were used for a preclinical assessment of nanosecond laser treatment.
Glyn Chidlow   +3 more
wiley   +1 more source

Intravitreal Dexamethasone Implantation in Intravitreal Bevacizumab Treatment-resistant Pseudophakic Cystoid Macular Edema [PDF]

open access: yesKorean Journal of Ophthalmology, 2019
To evaluate the changes in visual acuity (VA) and central macular thickness (CMT) after intravitreal dexamethasone (IVD) implantation in intravitreal bevacizumab (IVB) treatment-resistant cases with pseudophakic cystoid macular edema (PCME).This study included 10 PCME cases who underwent uneventful phacoemulsification and intraocular lens implantation ...
Altintas, Ayse Gul Kocak, Ilhan, Cagri
openaire   +2 more sources

USP25 promotes ferroptosis in diabetic retinopathy by deubiquitinating p53 and suppressing the GPX4/SLC7A11 axis

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Objective To explore the expression of the deubiquitinase (DUB) USP25 in diabetic retinopathy (DR) and its mechanistic role in regulating ferroptosis. Methods Bioinformatics was used to screen for DR‐related DUB candidate genes. USP25 expression was validated in a streptozotocin‐induced diabetic mouse model and high glucose (HG)‐treated ARPE ...
Yanjun Gao   +3 more
wiley   +1 more source

Efficacy of 0.2% povidone‐iodine and 0.1% polyhexamethylene biguanide as preoperative antiseptics in equine ophthalmic procedures

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 438-447, March 2025.
Abstract Objective This retrospective study evaluates the efficacy of povidone‐iodine (PI) and polyhexamethylene biguanide (PHMB) as preoperative antiseptics in equine ophthalmic procedures. Animals Studied Horses that underwent routine ophthalmic surgery and procedures.
Anna Farkas   +4 more
wiley   +1 more source

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