Results 121 to 130 of about 715,934 (265)

Early high‐dose aflibercept 8 mg clinical outcomes in wet age‐related macular degeneration patients resistant to aflibercept 2 mg or faricimab

Acta Ophthalmologica, EarlyView.
Pinja Sutinen, Idan Hecht, Raimo Tuuminen   +2 more
wiley   +1 more source

Mesenchymal Stem Cell‐Derived Extracellular Vesicles Ameliorate NaIO3‐Induced Dry AMD by Delivering miR‐486‐3p to Inhibit Lipocalin‐2‐Mediated Ferroptosis

MedComm, Volume 7, Issue 10, October 2026.
Our study reveals a novel mechanism by which MSC‐derived EVs alleviate NaIO3‐induced dry AMD‐like pathology. MSC‐EVs deliver miR‐486‐3p into retinal cells to directly inhibit the ferroptosis‐promoting target gene Lcn2. Concurrently, downregulated Lcn2 restores intracellular Gpx4 expression, thereby suppressing ferroptosis and rescuing retinal ...
Zheng Li, Tujing Zhao, Lin Ye, Runze Li, Huaping Tian, Ruilin Liao, Lulin Huang   +6 more
wiley   +1 more source

Intravitreal anti-VEGF injection for the treatment of progressive juxtapapillary retinal capillary hemangioma: a case report and mini review of the literature

, 2013
Elias Chelala, Ali Dirani, Ali Fadlallah Saint-Joseph University, Faculty of Medicine, Beirut, Lebanon Abstract: We report a case of a patient known to have a von Hippel–Lindau disease with documented progressive juxtapapillary retinal capillary ...
Dirani A, Chelala E, Fadlallah A
core  

Evaulation of Incidence and Risk Factors for Intraocular Pressure Elevation After Intravitreal Triamcinolone Acetonide Injection

, 2015
Objectives: To investigate the effect of intravitreal triamcinolone acetonide (IVTA) used for the macular edema on intraocular pressure (IOP) and to determine the risk factors for IOP elevation.
Cansu Yüksel-Elgin, Didar Uçar, Yildirim, Yeliz, Sema Arvas, Pınar Sultan, Funda Dikkaya, Ahmet Murat Sarıcı, Sultan, Pinar, Yeliz Yıldırım, Ucar, Didar, Yuksel-Elgin, Cansu, Dikkaya, Funda, Arvas, Sema, Sarici, Ahmet Murat   +13 more
core   +1 more source

Early Worsening of Diabetic Retinopathy Following Initiation of Hybrid Closed‐Loop/Automated Insulin Delivery Systems in Type 1 Diabetes: A Systematic Review and Structured Study‐Level Synthesis

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8878-8894, October 2026.
ABSTRACT Background Hybrid closed‐loop (HCL) systems achieve rapid, algorithm‐driven improvements in glycaemia in type 1 diabetes (T1D). Paradoxically, rapid improvement in glycaemic control is associated with early worsening of diabetic retinopathy (EWDR), a phenomenon established in the intensive insulin therapy era.
Matthew Anson, Ahmed Iqbal, Shazli Azmi, Philip Weston, Lucy Hughes, Mahreen Choudhury, David M. Hughes, Yalin Zheng, Philip I. Burgess, Uazman Alam   +9 more
wiley   +1 more source

Exogenous group G Streptococcus endophthalmitis following intravitreal ranibizumab injection

, 2012
Suleyman Kugu,1 Mehmet Sahin Sevim,2 Nilufer Zorlutuna Kaymak,1 Gurkan Erdogan,3 Baran Kandemir,1 Omer Kamil Dogan41Lutfi Kirdar Kartal Training and Research Hospital, Eye Clinic, Istanbul, 2Haydarpasa Numune Training and Research Hospital, Eye Clinic ...
Kaymak NZ, Sevim MS, Kandemir B, Dogan OK, Kugu S, Erdogan G   +5 more
core  

PEBP1 Regulates Ferroptosis in Acute Glaucoma: Targeted Therapy Using Engineered Exosomes

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
General schematic diagram of Spatial and Single‐Cell Transcriptomics Identifies PEBP1 as a Ferroptosis Mediator in Glaucoma: Targeted Intervention by Engineered Stem Cell Exosomes. ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide, primarily driven by the progressive loss of retinal ganglion cells (RGCs) under pathological high
Yijia Huang, Di Gong, Junhong Guo, Wei Huang, Tingyu Hu, Shengbin Tang, Li Li, Bingkai Feng, Kuanrong Dang, Simin Deng, Yong Liu, Chunyan Tan, Fei Yao, Jiantao Wang   +13 more
wiley   +1 more source

Anterior segment changes following intravitreal bevacizumab injection for treatment of neovascular glaucoma

, 2011
MI Canut1, A Alvarez2, J Nadal3, R Abreu4, JA Abreu5, JS Pulido61Glaucoma Section, 2Barraquer Ophthalmology Centre, 3Retina and Vitreous Unit, Macula Section, Institut Universitari Barraquer, Universidad Autonoma de Barcelona, Barcelona, Spain; 4Retina ...
Pulido JS, Abreu R, Alvarez A, Abreu JA, Canut MI, Nadal J   +5 more
core  

Pseudohypopyon Following Intravitreal Triamcinolone Acetonide Injection

, 2004
Objective: To report a case of a pseudohypopyon that developed after intravitreal injection of triamcinolone acetonide for choroidal neovascularization from age-related macular degeneration. Methods: Observational case report.
Lai, WW, Sharma, MC, Shapiro, MJ
core   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source