Results 201 to 210 of about 1,540,879 (346)

Reduced Neuronal Self‐Avoidance in Mouse Starburst Amacrine Cells With Only One Pcdhg Isoform

open access: yesDevelopmental Neurobiology, Volume 86, Issue 1, January 2026.
ABSTRACT The clustered protocadherins (cPcdhs) are a family of ∼60 homophilic cell adhesion molecules expressed across three gene clusters (Pcdha, Pcdhb, and Pcdhg) with a variety of essential roles in the developing nervous system. Some of these roles rely on specific isoforms, whereas others are more consistent with a model of isoform redundancy or a
Cathy M. McLeod   +4 more
wiley   +1 more source

Efficacy and Safety of Glycosidic Enzymes for Improved Gene Delivery to the Retina following Intravitreal Injection in Mice [PDF]

open access: gold, 2017
Jasmina Cehajic‐Kapetanovic   +4 more
openalex   +1 more source

Targeting the NEK7/NLRP3 Inflammasome Axis: Synergistic Protection of Intravitreal MCC950 and Systemic Metformin Against Diabetic Retinopathy in Rats

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Graphical Abstract ABSTRACT Objective Diabetic retinopathy (DR) is characterised by chronic neuroinflammation where the NLRP3 inflammasome plays a pivotal role. This study investigated the therapeutic potential and underlying mechanism of combining systemic metformin (MET) with intravitreal MCC950, a specific NLRP3 inhibitor, in a rodent model of DR ...
Kexuan Ren, Xiaofeng Li
wiley   +1 more source

[Intravitreal injections during anticoagulant treatment].

open access: yesKlinische Monatsblatter fur Augenheilkunde, 2008
The number of intravitreal injections has increased steadily over the past few years. The aim of this prospective study was to evaluate the safety of intravitreal injections in patients under concurrent oral anticoagulation or antiplatelet therapy.57 patients who underwent consecutively 80 intravitreal injections of Ranibizumab, Bevacizumab or ...
Horn, W. C., Hoerauf, Hans
openaire   +2 more sources

Driving Innovation: The Impact of National Health Policies on Optometry Research in East Asia

open access: yesThe International Journal of Health Planning and Management, Volume 41, Issue 1, Page 37-46, January 2026.
ABSTRACT This study examines the optometric research landscape in three East Asian countries—China, Japan, and Korea—analysing how research trends align with each country's national health strategies. By evaluating published articles and reviews from national journals between 2006 March 2025, we identify key areas of focus, including paediatric ...
Jihye Ahn, Moonsung Choi
wiley   +1 more source

Molecular Variations in Glycoprotein B of Asian Human Cytomegalovirus: Potential Impact on Virus Entry and Immune Evasion in Ocular Diseases

open access: yesJournal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Human cytomegalovirus (HCMV)‐associated ocular diseases have gained increasing attention due to a recent rise in cases diagnosed in Asia. A glycoprotein encoded by the virus UL55 gene, glycoprotein B (gB), is essential for viral entry and a primary target for naturally‐produced antibodies and vaccine development.
Tantri Lestari   +28 more
wiley   +1 more source

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