Results 91 to 100 of about 1,525,008 (304)

Image analysis method for measurement and prediction of intra‐matrix IgG diffusion

Biotechnology Progress, EarlyView.
Experimental and image analysis workflow for b‐IgG diffusion in hyaluronic acid (HA) matrix. Abstract Measurement and imaging of intra‐matrix protein therapeutics diffusion is important due to the emergence of injectable biologics currently in various stages of research and clinical testing.
Riya Debbarma, Antonio C. F. dos Santos, Michael Ladisch   +2 more
wiley   +1 more source

The Role of Steroids in the Management of Macular Edema from Retinal Vein Occlusion

Oftalʹmologiâ, 2019
Aim: To analyze the effectiveness of intravitreal injection of an anti-VEGF agent (ranibizumab) and an dexametazon implant for the intravitreal injection, in real clinical life. Patients and Methods.
M. V. Budzinskaya, A. V. Shelankova, A. A. Plukhova, N. M. Nuriyeva, A. S. Sorokin   +4 more
doaj   +1 more source

Diffusion through the ex vivo vitreal body - bovine, porcine, and ovine models are poor surrogates for the human vitreous [PDF]

, 2018
© 2018 The Authors. Published by Elsevier B.V.The human vitreous humour is a complex gel structure whose composition and physical properties can vary considerably from person to person and also change with age. To date, the viscoelastic properties of the
Brown, Marc, Chau, David, Cook, Michael, Hutter, Victoria, Shafaie, Sara   +4 more
core   +4 more sources

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

A simulation tool for better management of retinal services [PDF]

, 2018
Background: Advances in the management of retinal diseases have been fast-paced as new treatments become available, resulting in increasing numbers of patients receiving treatment in hospital retinal services.
A Kotecha, A Kotecha, Aimee Verner, Andriy Danyliv, CG Owen, David Southern, Eren Demir, FG Holz, GA Lalwani, HR Wright, JA Haller, K Hatz, Karsten Kortuem, Katja Hatz, KT Tsaousis, Line Kvannli, OP Gupta, RB Rush, S Trikha, W Amoaku, Winfried Amoaku   +20 more
core   +2 more sources

Same-Day Bilateral Intravitreal Anti-Vascular Endothelial Growth Factor Injections: Experience of a Large Canadian Retina Center

Ophthalmologica, 2019
Objective: To evaluate the outcomes and complications of bilateral same-day intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections.
V. Juncal, Carolina L. M. Francisconi, F. Altomare, D. Chow, L. Giavedoni, R. Muni, A. Berger, D. Wong   +7 more
semanticscholar   +1 more source

Associations Between Initial Glycated Hemoglobin at Diabetes Diagnosis, Longitudinal Changes and Medication Effects, and the Severity and Progression of Sight‐Threatening Diabetic Retinopathy

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic retinopathy (DR) is a leading cause of vision impairment in patients diagnosed with Type 2 diabetes mellitus (T2DM). Awareness of risk factors is necessary to reduce or prevent harmful effects of DR such as irreversible vision loss, and to help ensure early treatment.
Yu‐Chi Sung, Yu‐Kuang Chen, Ching‐An Chen, Pei‐Kang Liu, Kai‐Chun Cheng, Wei‐Shan Chang, Chia‐Li Tseng, Hui‐Min Hsieh, Shwu‐Jiuan Sheu   +8 more
wiley   +1 more source

Branch Retinal Vein Occlusion, Macular Ischemia, and Intravitreal Anti-VEGF Therapy

Case Reports in Ophthalmology, 2017
Purpose: To report a case with ischemic macular edema (ME) due to an acute branch retinal vein occlusion (BRVO) which was treated with repeated intravitreal anti-VEGF injections. Methods: Retrospective case presentation.
Thomas Bertelmann, Hans Ulrich Frank, Hendrik Ansgar Fuchs, Nicolas Feltgen   +3 more
doaj   +1 more source

Dynamic Retinal Pathology in Glaucoma Progression Revealed by High‐Resolution Functional Imaging in Vivo

Laser &Photonics Reviews, EarlyView.
In this work, we investigated the dynamic retinal pathology of glaucoma from onset to late stages through longitudinal in vivo high‐resolution imaging in a silicone oil‐induced ocular hypertension (SOHU) glaucoma mouse model. We developed an optimized adaptive optics two‐photon excitation fluorescence microscopy (AO‐TPEFM) technique for morphological ...
Yiming Fu, Pham Binh Minh, Sicong He, Yingzhu He, Zhongya Qin, Ting Xie, Jianan Qu   +6 more
wiley   +1 more source

Evaluation of the Vascular Density, the Area of Foveal Avascular Zone, and Corrected Vision in Patients with Diabetic Macular Edema after Anti-VEGF Therapy

پزشکی بالینی ابن سینا, 2023
Background and Objective: This study aimed to evaluate the changes in macular superficial and deep capillary plexus (SCP and DCP) density, Foveal Avascular Zone (FAZ) area, and visual acuity in patients with diabetic macular edema after anti-VEGF therapy.
Alireza Maleki, Kayhan Khani Ali Akbari, Narjes Sargolzaie   +2 more
doaj