Results 91 to 100 of about 1,516,429 (359)

Comparison of 12-month therapeutic effect of conbercept and ranibizumab for diabetic macular edema: a real-life clinical practice study

open access: yesBMC Ophthalmology, 2017
Background To compare the efficacy of intravitreal conbercept and ranibizumab in the treatment of diabetic macular edema (DME) in a real-life clinical practice. Methods This was a retrospective study.
Yule Xu   +4 more
doaj   +1 more source

PHOSPHO1 Suppresses Ferroptosis in Retinal Pigment Epithelial Cells by Reducing the Levels of Phosphatidylethanolamine Molecular Species

open access: yesAdvanced Science, EarlyView.
Iron‐induced lipid peroxidation of phosphatidylethanolamine (PE) species is the key driver of ferroptosis. The authors discovered that PHOSPHO1 lowers the level of PE in retinal pigment epithelial cells thus reducing the formation of lipid peroxides. Lowering PE levels can also prevent the creation of autolysosomes, reduce the production of free iron ...
Zhiyang Chen   +19 more
wiley   +1 more source

Intravitreal injections of anti-VEGF agents and antibiotic prophylaxis for endophthalmitis: A systematic review and meta-analysis

open access: yesScientific Reports, 2017
We performed a systematic review and meta-analysis to determine whether the use of local antibiotics is a beneficial prophylactic treatment for endophthalmitis in patients treated with anti-VEGF agents.
M. Bande   +6 more
semanticscholar   +1 more source

Treatment as required versus regular monthly treatment in the management of neovascular age-related macular degeneration: a systematic review and meta-analysis [PDF]

open access: yes, 2015
Background: To investigate whether treatment as required ‘pro re nata’ (PRN) versus regular monthly treatment regimens lead to differences in outcomes in neovascular age-related macular degeneration (nAMD).
Agostini, Hansjuergen   +7 more
core   +3 more sources

Three versus five intravitreal aflibercept injections as the initial loading phase in the treatment of diabetic macular edema: one-year results [PDF]

open access: yes, 2020
Purpose: To compare the efficacy of three initial monthly intravitreal aflibercept injections followed by pro re nata (3+PRN) dosing versus five initial monthly intravitreal aflibercept injections followed by pro re nata (5+ PRN) dosing in patients with ...
Bölükbaşı, Selim   +6 more
core   +1 more source

Applying Lucentis for the treatment of retinopathy of prematurity

open access: yesРоссийский офтальмологический журнал, 2022
Purpose: to evaluate the efficacy of Lucentis for the treatment of retinopathy of prematurity (ROP). Material and methods. 51 infants (102 eyes) with the gestational age between 24 and 33 weeks were given intravitreal injections of Lucentis, All patients
S. V. Lesovoy, O. A. Boginskaya
doaj   +1 more source

An in vivo evaluation of Brilliant Blue G in animals and humans [PDF]

open access: yes, 2008
Background/Aims: To evaluate the retinal toxicity of Brilliant Blue G (BBG) following intravitreal injection in rat eyes and examine the biocompatibility and the staining properties in humans.Methods: BBG was injected into the 11 rat eyes to evaluate ...
Fiedorowicz, M.   +10 more
core   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Evaluation of pain during intravitreal Ozurdex injections vs intravitreal bevacizumab injections [PDF]

open access: yesEye, 2014
The purpose was to evaluate the pain associated with intravitreal Ozurdex injections, and to compare it with that associated with intravitreal bevacizumab injections.The study included 57 eyes of 57 patients who received an intravitreal Ozurdex injection at our institution. Pain was measured by the visual analog scale (VAS).
Michael Regenbogen   +5 more
openaire   +2 more sources

Analyzing the Carbon Footprint of an Intravitreal Injection

open access: yesJournal of Ophthalmic and Vision Research, 2021
Purpose: To estimate the carbon footprint of a single intravitreal injection in a hospital-based intravitreal service. Methods: Greenhouse gas emissions attributable to the delivery of an intravitreal injection were calculated using a hybrid lifecycle analysis technique.
Power, B, Brady, R, Connell, P
openaire   +6 more sources

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