Results 41 to 50 of about 138,063 (253)

"Good-but-Imperfect" electromagnetic reverberation in a VIRC [PDF]

, 2011
Novel theoretical probability density functions (PDF) of electromagnetic fields inside reverberation chambers operating in a “good-but-imperfect‿ regime have been recently reported. The present work reports on the application and assessment of these PDFs
Canavero, F., Flavio Canavero, Leferink, Frank Bernardus Johannes; id_orcid, Ramiro Serra, Leferink, F.B.J., Frank Leferink, Leferink, Frank Bernardus Johannes, Leferink F., Leferink, F., Serra, Ramiro, Serra, R., Canavero, Flavio, Serra R.   +12 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

RESEARCH ON FAULT DIAGNOSIS METHOD OF ROLLING BEAR BASED ON SYMBOLIC ANALYSIS OF INTRINSIC MODE FUNCTION

, 2016
A fault diagnosis method of the intrinsic mode components symbolic analysis is proposed on the basis of empirical mode decomposition. Firstly,the extension fault signal is decomposed into several intrinsic mode functions under different time scales with ...
HOU HePing, LIU Kai, XU ZhuoFei
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Feature Extraction of Ship-Radiated Noise Based on Permutation Entropy of the Intrinsic Mode Function with the Highest Energy

, 2016
In order to solve the problem of feature extraction of underwater acoustic signals in complex ocean environment, a new method for feature extraction from ship-radiated noise is presented based on empirical mode decomposition theory and permutation ...
Yu-Xing Li, Xiao Chen, Zhe Chen, Ya-An Li   +3 more
core   +1 more source

Thermal Image Enhancement using Bi-dimensional Empirical Mode Decomposition in Combination with Relevance Vector Machine for Rotating Machinery Fault Diagnosis [PDF]

, 2009
In this study, a novel fault diagnosis system for rotating machinery using thermal imaging is proposed. This system consists of bi-dimensional empirical mode decomposition (BEMD) for image enhancement, a generalized discriminant analysis (GDA) for ...
Yang, Bo-Suk, Gu, Fengshou, Ball, Andrew, Al-Ani, A, Yang, Bo Suk, Tran, Van Tung, Al-Jumaily, A, Khushaba, RN   +7 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Reconstructed Phase Spaces of Intrinsic Mode Functions. Application to Postural Stability Analysis

, 2006
International audienceIn this contribution, we propose an efficient nonlinear analysis method characterizing postural steadiness. The analyzed signal is the displacement of the centre of pressure (COP) collected from a force plate used for measuring ...
Snoussi, Hichem, David Hewson, Michel Doussot, Hassan Amoud, Doussot, Michel, Jacques Duchene, Duchene, Jacques, Hewson, David, Amoud, Hassan, Hichem Snoussi   +9 more
core   +1 more source