Results 71 to 80 of about 683,504 (300)
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Intrinsic Safety — The Second Edition
Measurement and Control, 1990 The second edition of the European Standard for Intrinsic Safety was released for public comment in early 1989 and contains several significant additions and clarifications which could have a significant effect on the design of intrinsically-safe apparatus and systems.
openaire +2 more sources
Intrinsic Safety of Capacitive-Resistive Circuit.
Shigen-to-Sozai, 1994 Electric-arc ignition test of methane gas has been carried out for some capacitive-resistive circuit models. The results of the minmum ignition voltages (Vm) for circuits with paticular parameters and with the discharged energy values, has been evaluated.
Hironori HANEDA, Yasumori TAKAHASHI
openaire +2 more sources
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
, 2018 Autonomous robots need to interact with unknown, unstructured and changing environments, constantly facing novel challenges. Therefore, continuous online adaptation for lifelong-learning and the need of sample-efficient mechanisms to adapt to changes in ...
Peters, Jan +2 more
core +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Fighting the flow: the stability of model flocks in a vortical flow
, 2016 We investigate the stability of self-propelled particle flocks in the Taylor-Green vortex, a steady vortical flow. We consider a model where particles align themselves to a combination of the orientation and the acceleration of particles within a ...
Baggaley, Andrew W.
core +1 more source
Landslide risk management through spatial analysis and stochastic prediction for territorial resilience evaluation [PDF]
, 2019 Natural materials, such as soils, are influenced by many factors acting during their formative and evolutionary process: atmospheric agents, erosion and transport phenomena, sedimentation conditions that give soil properties a non-reducible randomness by
Cardarilli, M. +2 more
core +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source