Results 61 to 70 of about 204,714 (304)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Analysis of influencing factors of short-circuit spark discharge in electric potential capacitance circuit

open access: yesGong-kuang zidonghua, 2020
Most of existing models and methods for research of capacitive circuit spark discharge and high-power intrinsic safety power supply only consider discharge characteristics of energy storage elements during discharge process, and do not consider influence
KANG Qian   +3 more
doaj   +1 more source

Extrinsic Safety Systems [PDF]

open access: yes, 2000
PresentationEverything dies, breaks, or runs out of gas. Everything. This is especially true for extrinsic safety systems. In contrast to intrinsic safety in which the process is designed to be inherently safe (1), extrinsic safety involves the addition ...
Summers, Angela E.
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Psychological Safety and Employee Voice in IT Sector: Parallel Mediation Effect of Affective Commitment and Intrinsic Motivation

open access: yes, 2020
The study is an attempt to explain the relationship ofpsychological safety on employee voice behaviour byexamining the mediating role of affective commitmentand intrinsic motivation.
Soumyaja, Devi, Kuriakose, Jeeva
core   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

Intrinsic Safety — The Second Edition

open access: yesMeasurement and Control, 1990
The second edition of the European Standard for Intrinsic Safety was released for public comment in early 1989 and contains several significant additions and clarifications which could have a significant effect on the design of intrinsically-safe apparatus and systems. The purpose of this article is to highlight these proposals and examine their likely
openaire   +2 more sources

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang   +22 more
wiley   +1 more source

Intrinsic Safety of Capacitive-Resistive Circuit.

open access: yesShigen-to-Sozai, 1994
Electric-arc ignition test of methane gas has been carried out for some capacitive-resistive circuit models. The results of the minmum ignition voltages (Vm) for circuits with paticular parameters and with the discharged energy values, has been evaluated.
HANEDA, Hironori, TAKAHASHI, Yasumori
openaire   +2 more sources

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