Results 41 to 50 of about 3,062,805 (297)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

A new approach for bin packing problem using knowledge reuse and improved heuristic

Scientific Reports
The two-dimensional (2D) irregular packing problem is a combinatorial optimization problem with NP-complete characteristics, which is common in the production process of clothing, ships, and plate metals.
Jie Fang, Xubing Chen, Yunqing Rao, Yili Peng, kuan Yan   +4 more
doaj   +1 more source

Research on Hydrodynamic Performance of a 30 kW Rim-Driven Thruster and Its Coupling Mechanism with an AUV

Journal of Marine Science and Engineering
With the continuous expansion of deep-sea resource exploration, marine environmental monitoring, and underwater operations, Autonomous Underwater Vehicles (AUVs) have been increasingly widely applied.
Xia Yang, Kunkun Li, Xiong Deng, Dingfeng Yu, Yiyun Peng, Yan Luo, Yanyang Wu   +6 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Design and Analysis of a Surface Capture Device Under Moderate Sea State 4

Journal of Marine Science and Engineering
To address the limitations of poor adaptability and insufficient versatility of current surface capture technologies for autonomous underwater vehicles (AUVs) under high sea state conditions, this study proposes an ROV-based capture system equipped with ...
Xiong Deng, Linfeng Li, Xia Yang, Dingfeng Yu, Yiyun Peng, Yan Luo, Yanyang Wu   +6 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Research on High-Precision Prediction of Vertical Hydrodynamic Coefficients for AUV Based on CFD and GA-BP Neural Network

Mathematics
Aiming at the engineering pain points of insufficient sample size, inadequate working condition coverage, and poor generalization performance in traditional solution methods of vertical hydrodynamic coefficients for Autonomous Underwater Vehicles (AUVs),
Dingfeng Yu, Xi Zhang, Xia Yang, Yiyun Peng, Xiong Deng, Yan Luo, Yanyang Wu   +6 more
doaj   +1 more source

Intrinsic Safety — The Second Edition

Measurement and Control, 1990
The second edition of the European Standard for Intrinsic Safety was released for public comment in early 1989 and contains several significant additions and clarifications which could have a significant effect on the design of intrinsically-safe apparatus and systems. The purpose of this article is to highlight these proposals and examine their likely
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Structural Design and Performance Analysis of Underwater Tethered Vehicles

Journal of Marine Science and Engineering
An underwater towed vehicle serves as an effective and widely applicable mobile marine observation platform. Existing towed vehicles rely heavily on cables for depth adjustment.
Yan Luo, Xinming Xiong, Xia Yang, Xiong Deng, Dingfeng Yu, Yiyun Peng, Yanyang Wu   +6 more
doaj   +1 more source