Results 41 to 50 of about 204,714 (304)

Several Methods of Reducing Discharge Energy for Intrinsic Safety Power Supply

open access: yes, 2020
In order to reduce the discharge spark energy of the intrinsic safety power supply, several measures are proposed in this paper. When the over-current protection occurs, DC-DC or AC-DC module should be turned off as quickly as possible, and the switching
DONG Jianguo, LI Yanmin, ZHOU Xingdong, ZHANG Lei
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Heat Transfer Performance and Flow Characteristics of Helical Baffle–Corrugated Tube Heat Exchanger

open access: yesApplied Sciences
Heat exchangers are widely used in petrochemical and other industries. Improving the efficiency of heat exchangers to increase energy utilization is crucial.
Junwen Cheng   +3 more
doaj   +1 more source

Research on explosion-proof technology for coal mine rescue robot

open access: yesGong-kuang zidonghua, 2019
The paper introduced general situation of explosion-proof technology of coal mine rescue robot, and summarized the research status and application of explosion-proof technology of coal mine rescue robot at home and abroad, and pointed out some progress ...
ZHENG Xuezhao   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Research on surge protection technology of coal mine safety monitoring system

open access: yesGong-kuang zidonghua, 2018
The conventional surge protection technology was introduced. Based on theoretical research and standard test of electromagnetic compatibility surge protection technology in coal mine safety monitoring system, it was indicated that the conventional surge ...
ZHANG Ziliang
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Experimental study on performance of rectangular groove phase change thermal storage system with pressure-enhanced contact melting

open access: yesCase Studies in Thermal Engineering
Contact melting (CM) enables the formation of an ultrathin liquid film between the phase change material (PCM) and the heated surface, where the extremely low thermal resistance (TR) ensures superior thermal conductivity (TC).
Junkai Li   +5 more
doaj   +1 more source

Overview of Problems and Solutions in the Design of Intrinsically Safe Apparatuses

open access: yesElektronika ir Elektrotechnika, 2023
The article presents selected basic problems occurring in the design of intrinsically safe apparatuses, solutions to some of them, and points out mistakes made during their design.
Sławomir Chmielarz   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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