Results 21 to 30 of about 197,579 (259)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Analysis of Maritime Traffic Safety Based on Intrinsic Safety Theory

Journal of Physics: Conference Series, 2021
Abstract Strengthening intrinsic safety of maritime traffic is essential for further modernization of the maritime traffic safety governance system and the governance capabilities. This paper studies the connotations of the intrinsic safety of maritime traffic, then analyzes the composition of the intrinsic safety system of maritime ...
Jiang Lili, Ma Minglu
openaire   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

DART – Advanced Intrinsic Safety

International Journal of Power System Operation and Energy Management, 2012
Intrinsic safety (I.S) is a worldwide accepted standard to protect low power electrical circuits from the potentially explosive hazardous area. End users throughout the fieldbus world are demanding more power to connect more instruments to their Fieldbus segments in Class I, Division 1, and Class I, Division 2, hazardous location applications.
Nilima Warke, Madhavi Talar
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Applications of Phyllosilicates Mineral Powder as Anti-Wear Lubricating Materials in Lubricating Oil and Grease: A Review

Lubricants
Wear caused by friction is one of the main causes of most mechanical component failures. The application of powders as anti-wear lubricating materials has achieved great advances, which are of great significance in reducing friction and wear. This review
Nan Jiang, Feng Nan
doaj   +1 more source

Design of mine-used intrinsically safe line array X-ray receiving box

Gong-kuang zidonghua, 2021
The mine-used explosion-proof line array X-ray receiving box is not suitable for nondestructive testing of high-speed conveyor belts. And there are difficulties in processing the explosion-proof enclosure and heavy weight for nondestructive detection of ...
FANG Chongquan
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Efficient and long-acting corrosion inhibition mechanisms and adsorption behavior of sodium laurate on AZ91D Mg alloy in oxalic acid solution

Results in Surfaces and Interfaces
To address the severe corrosion of Mg alloys caused by oxalic acid generated by high-temperature oxidation in automotive engine coolant, this study employed electrochemical testing, surface characterizations, and theoretical calculations to investigate ...
Jinbei He, Hualiang Huang, Xiaotao Zheng
doaj   +1 more source