Results 31 to 40 of about 212,876 (197)

Optimization Design of Intrinsic Safety Pilot Circuit for Motor Remote Start and Stop

open access: yesMeikuang Anquan, 2020
This paper introduces the types of remote starting and stopping pilot circuits of existing motors, the existence of mis-starting, the inability to identify all line faults and the unstable operation of power supply voltage reduction, and proposes an ...
ZHANG Yuxiang, SONG Jiancheng, TIAN Muqin
doaj   +1 more source

Intrinsic power supply [PDF]

open access: yes, 2014
Tato práce se zabývá vývojem jiskrově bezpečného zdroje určeného pro napájení zařízení v prostorách s nebezpečím výbuchu. V souvislosti s tím jsou v práci vysvětleny pojmy související s jiskrovou bezpečností.
Wurzel, Tomáš
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Supporting Solidarity

open access: yesVoices in Bioethics, 2023
Photo ID 72893750 © Rawpixelimages|Dreamstime.com ABSTRACT Solidarity is a concept increasingly employed in bioethics whose application merits further clarity and explanation.
Claire Moore   +2 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Design of a type of intrinsic safety miner lamp with identification card

open access: yesGong-kuang zidonghua, 2013
In view of problems that equipments carried by underground miner increase because of individual design and power supply of identification card, and sometimes positioning would fail because that charging or change of battery of identification card are not
HUO Yin-jia, GU Yi-dong
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Risk management and the stratification of logistics service provision [PDF]

open access: yes, 2011
This paper stems from a research project undertaken between 2007 and 2010. It discusses the development of supply chain management together with the understanding of the impact of supply chain risk. It gives an overview of the increasing stratification
Gibson, R.   +3 more
core  

Bistable Mechanisms 3D Printing for Mechanically Programmable Vibration Control

open access: yesAdvanced Engineering Materials, EarlyView.
This work introduces a 3D‐printed bistable mechanism integrated into tuned mass dampers (TMDs) for mechanically adaptive passive vibration suppression. Through optimized geometry, the bistable design provides adaptable vibration reduction across a broad range of scenarios, achieving effective vibration mitigation without complex controls or external ...
Ali Zolfagharian   +4 more
wiley   +1 more source

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