Results 31 to 40 of about 214,165 (250)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Voices in Bioethics, 2023 Photo ID 72893750 © Rawpixelimages|Dreamstime.com ABSTRACT Solidarity is a concept increasingly employed in bioethics whose application merits further clarity and explanation.
Claire Moore +2 more
doaj +1 more source
A goal programming methodology for multiobjective optimization of distributed energy hubs operation [PDF]
, 2014 This paper addresses the problem of optimal energy flow management in multicarrier energy networks in the presence of interconnected energy hubs. The overall problem is here formalized by a nonlinear constrained multiobjective optimization problem and ...
A. Vaccaro +16 more
core +2 more sources
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Design of a type of intrinsic safety miner lamp with identification card
Gong-kuang zidonghua, 2013 In view of problems that equipments carried by underground miner increase because of individual design and power supply of identification card, and sometimes positioning would fail because that charging or change of battery of identification card are not
HUO Yin-jia, GU Yi-dong
doaj +1 more source
LC-VCO design optimization methodology based on the gm/ID ratio for nanometer CMOS technologies [PDF]
, 2011 In this paper, an LC voltage-controlled oscillator (LC-VCO) design optimization methodology based on the gm/ID technique and on the exploration of all inversion regions of the MOS transistor (MOST) is presented.
Fiorelli, Rafaella +2 more
core +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
A Single-Stage Isolated Battery Charger Using Nonbridged Positive Cuk Converter Configuration
IET Electrical Systems in Transportation, 2023 This article presents a nonbridged isolated positive Cuk (NB-IPCuk) converter-based single-stage battery charging system (SSBCS). The architecture of the suggested charger ensures the intrinsic advantage of power quality improvement in discontinuous ...
Tanmay Shukla +2 more
doaj +1 more source