Results 61 to 70 of about 2,198,841 (282)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Humans’ Best Friend? The Ethical Dilemma of Pets
Relations, 2013 The main aim of this paper is to demonstrate the need for a reassessment of the moral status of pets. I argue that pets rest on an undefined ethical borderline, which brings several puzzling problems to both human-centered ethics and animal ethics and ...
Matteo Andreozzi
doaj +1 more source
Shot noise in diffusive ferromagnetic metals
, 2006 We show that shot noise in a diffusive ferromagnetic wire connected by tunnel contacts to two ferromagnetic electrodes can probe the intrinsic density of states and the extrinsic impurity scattering spin-polarization contributions in the polarization of ...
E. H. Hall +3 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Determining the Conceptual Geometry of Types of Value [PDF]
اخلاق وحیانی, 2012 The issue of virtue and evil of actions has been one of the most important and sect-creating issues in the history of scholastic and ethical thoughts. The numerous topics such as semantic description of virtue & evil of actions, ontological description ...
Ahmad Hossien Sharifi
doaj
Sign changes and resonance of intrinsic spin Hall effect in two-dimensional hole gas
, 2006 The intrinsic spin Hall conductance shows rich sign changes by applying a perpendicular magnetic field in a two-dimensional hole gas. Especially, a notable sign changes can be achieved by adjusting the characteristic length of the Rashba coupling and ...
Liu, Qin, Ma, Tianxing
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
AscaryaThe question addressed in this article is a possible new epistemological framework to find solutions to the current crisis. The analysis began with the idea of creation as a holistic concept.
Rüdiger Lohlker
doaj +1 more source