Results 1 to 10 of about 66,315 (318)

Looking at bacterial cell poles from a liquid-liquid phase separation of intrinsically disordered proteins perspective. [PDF]

Curr Res Struct Biol
Aldadah R, Lekic D, Sabanovic K, Kovalenko B, Adilovic M, Hromic-Jahjefendic A, Uversky VN.   +6 more
europepmc   +2 more sources

IDPsBind: a repository of binding sites for intrinsically disordered proteins complexes with known 3D structures

BMC Molecular and Cell Biology, 2022
Background Intrinsically disordered proteins (IDPs) lack a stable three-dimensional structure under physiological conditions but play crucial roles in many biological processes.
CanZhuang Sun, YongE Feng, GuoLiang Fan
doaj   +1 more source

idpr: A package for profiling and analyzing Intrinsically Disordered Proteins in R

PLoS ONE, 2022
Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are proteins or protein-domains that do not have a single native structure, rather, they are a class of flexible peptides that can rapidly adopt multiple conformations ...
William M. McFadden, Judith L. Yanowitz
doaj   +2 more sources

Investigating Intrinsically Disordered Proteins With Brownian Dynamics

Frontiers in Molecular Biosciences, 2022
Intrinsically disordered proteins (IDPs) have recently become systems of great interest due to their involvement in modulating many biological processes and their aggregation being implicated in many diseases.
Surl-Hee Ahn, Gary A. Huber, Gary A. Huber, J. Andrew McCammon, J. Andrew McCammon   +4 more
doaj   +1 more source

Protocol for detecting interactions between intrinsically disordered proteins and long DNA substrates by electrophoretic mobility shift assay. [PDF]

STAR Protoc
Pastic A, Kochhar A, D'Amours D.
europepmc   +2 more sources

Adenoviral E1A Exploits Flexibility and Disorder to Target Cellular Proteins

Biomolecules, 2020
Direct interaction between intrinsically disordered proteins (IDPs) is often difficult to characterize hampering the elucidation of their binding mechanism.
Maria Grazia Murrali, Isabella C. Felli, Roberta Pierattelli   +2 more
doaj   +1 more source

Evolutionary Study of Disorder in Protein Sequences

Biomolecules, 2020
Intrinsically disordered proteins (IDPs) contain regions lacking intrinsic globular structure (intrinsically disordered regions, IDRs). IDPs are present across the tree of life, with great variability of IDR type and frequency even between closely ...
Kristina Kastano, Gábor Erdős, Pablo Mier, Gregorio Alanis-Lobato, Vasilis J. Promponas, Zsuzsanna Dosztányi, Miguel A. Andrade-Navarro   +6 more
doaj   +1 more source

The N-terminal intrinsically disordered domain of mgm101p is localized to the mitochondrial nucleoid. [PDF]

, 2013
The mitochondrial genome maintenance gene, MGM101, is essential for yeasts that depend on mitochondrial DNA replication. Previously, in Saccharomyces cerevisiae, it has been found that the carboxy-terminal two-thirds of Mgm101p has a functional core ...
A Moya, A Schlessinger, AEA Hobbs, AK Dunker, AK Dunker, AM Waterhouse, B He, BA Kaufman, C Galea, CJ Brown, D Tillett, David C. Hayward, DF Bogenhagen, DF Bogenhagen, E Garner, GD Clark-Walker, George Desmond Clark-Walker, GW Daughdrill, H Dyson, H Hegyi, HJ Dyson, I Miyakawa, JD Nardozzi, JJ Ward, K Itoh, K Okamoto, K Peng, L Dente, M Ito, M Kucej, M Mbantenkhu, MA Larkin, MG Claros, MW Gray, P Tompa, PE Wright, RD Gietz, RW Gilkerson, S Meeusen, S Meeusen, Vladimir N. Uversky, X Chen, X Zuo, X Zuo, XJ Chen, Y Elbaz, Z Dosztányi, Z Dosztányi, Zsuzsanna Dosztányi   +48 more
core   +6 more sources

NeProc predicts binding segments in intrinsically disordered regions without learning binding region sequences

Biophysics and Physicobiology, 2020
Intrinsically disordered proteins are those proteins with intrinsically disordered regions. One of the unique characteristics of intrinsically disordered proteins is the existence of functional segments in intrinsically dis­ordered regions.
Hiroto Anbo, Hiroki Amagai, Satoshi Fukuchi   +2 more
doaj   +1 more source

A creature with a hundred waggly tails: intrinsically disordered proteins in the ribosome [PDF]

, 2013
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Dunker, A. Keith, Kurgan, Lukasz, Mizianty, Marcin J., Oldfield, Christopher J., Peng, Zhenling, Uversky, Vladmir N., Xue, Bin   +6 more
core   +2 more sources